The Effects of Trace Elements and Endocrine-Disrupting Compounds on Metabolic Health
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Environmental Metabolomics".
Deadline for manuscript submissions: 15 August 2026 | Viewed by 698
Editors
Interests: trace elements; micronutrients; dietary exposure; mineral bioavailability; trace element toxicity; nutritional determinants; food safety; health risk assessment; oxidative stress; element metabolism; human nutrition
Special Issues, Collections and Topics in MDPI journals
Interests: environmental toxicology; food safety; instrumental analysis; chemical contaminants (heavy metals, pesticides, PCBs, PAHs, and others) in food, beverages, drinking water, breast milk, and blood
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, entitled "The Effects of Trace Elements and Endocrine-Disrupting Compounds on Metabolic Health", is devoted to the role of trace elements and endocrine-active compounds in the proper functioning of human metabolic health.
Trace Elements can play a dual role in ensuring metabolic health: they can be essential (in which case it is necessary to ensure adequate levels in the body) but also insignificant or even harmful (in the case of toxic elements). Despite the proven impact of these elements on the development of inflammation in the body, oxidative stress, and the normal aging process of cells, their impact continues to be marginalized. Some of these elements, such as cadmium, lead, mercury, and arsenic, are also classified as endocrine-disrupting chemicals (EDCs).
Endocrine-disrupting compounds (including BPA, phthalates, pesticides, parabens, and PCBs) disrupt metabolic health by acting as endocrine disruptors, causing inflammation, oxidative stress, and altering the gut microbiota.
Trace elements and endocrine-disrupting compounds can damage cells, disrupt insulin signaling, interfere with energy utilization, and overload the body's detoxification systems, leading to an increased risk of obesity, type 2 diabetes, fatty liver disease, and insulin resistance.
When analyzing the importance of elements and endocrine-active substances in ensuring metabolic health, particular attention should be paid to the following:
- Dose–response relationships;
- Multi-element interactions;
- Individual variability (genetics, gender, diet, and environmental exposure).
Understanding all these aspects will contribute to the development of new targeted strategies for the prevention and treatment of metabolic disorders.
In light of recent findings, we invite you to submit articles on the impact of trace elements and endocrine-active substances on metabolic health.
Dr. Kamila Pokorska-Niewiada
Dr. Agata Witczak
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- the role of trace elements and/or EDCs in the development of metabolic syndrome
- trace elements and endocrine-active substances in biological samples, their potential use as biomarkers of metabolic disorders
- progress in research on multifactorial relationships determining metabolic health/development of metabolic diseases
- progress in clinical research on the importance of elements and EDCs in metabolic pathways
- the impact of genetic and environmental disorders on metabolite levels and fluxes
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