Zebrafish Models in the Study of Diabetes and Metabolic Dysfunction
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 51
Special Issue Editor
Special Issue Information
Dear Colleagues,
Zebrafish (Danio rerio) have gained prominence as a versatile and increasingly significant vertebrate model for investigating human metabolic conditions, including diabetes and obesity. Zebrafish serve as an exceptional model for exploring the molecular and cellular foundations of metabolic disorders. Their genetic and physiological parallels with mammals, combined with their external development, transparency during initial stages, and capacity for extensive drug screening, greatly enhance their value in research.
This Special Issue, entitled "Zebrafish Models in the Study of Diabetes and Metabolic Dysfunction", is dedicated to presenting pioneering research that utilizes zebrafish to investigate the development of metabolic disorders. We invite submissions of original research and review articles that explore the use of zebrafish models in studying hyperglycemia, insulin resistance, lipid metabolism disorders, pancreatic β-cell dysfunction, hepatic steatosis, and the effects of diet-induced metabolic stress. We particularly encourage studies that involve CRISPR/Cas9-based gene editing, transgenic models, and high-throughput screening of pharmacological or nutraceutical agents.
This issue aims to highlight the integration of metabolomics, transcriptomics, and imaging technologies to deepen our understanding of both systemic and organ-specific metabolic changes in zebrafish. By compiling a wide range of research contributions, this Special Issue will provide a thorough overview of how zebrafish are contributing to our knowledge of metabolic diseases and their potential treatment options. We eagerly anticipate your valuable contributions to this expanding and interdisciplinary field.
Dr. Liqing Zang
Guest Editor
Manuscript Submission Information
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Keywords
- zebrafish
- diabetes
- obesity
- metabolic dysfunction
- insulin resistance
- hyperglycemia
- lipid metabolism
- drug screening
- nutraceuticals
- gene editing
- high-fat diet
- metabolomics
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