Metabolomics: The Role of Natural Products in Drugs
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 960
Editors
Interests: metabolomics; natural products; drug discovery; bioactive metabolites; high-throughput screening; chemical biology; ocular pharmacology; computational metabolite profiling
Interests: natural products; phytochemistry; propolis (green, red, brown); bioactive compounds; phenolic compounds; analytical chemistry; hplc-uv; gc-ms; chemical characterization; volatile oils; fractionation techniques; antimicrobial activity; antiviral activity; antiplasmodial activity; leishmanicidal activity; cytotoxicity; cancer models; nanoparticles; toxicology; in vivo pharmacology; gastroprotection; wound healing; stability studies; guttiferones; botanical sources; drug discovery from natural products
Special Issue Information
Dear Colleagues,
Natural products have long served as a foundation for drug discovery, providing structurally diverse and biologically active compounds that continue to inspire modern therapeutics. In recent years, advances in metabolomics have transformed our ability to characterize the chemical diversity of natural matrices, understand bioactive metabolite functions, and uncover novel molecules with pharmaceutical potential. High-resolution analytical platforms, computational approaches, and integrative multi-omics are accelerating the identification, quantification, and mechanistic interpretation of natural products within complex biological systems.
Metabolomics offers unparalleled power to elucidate metabolic signatures associated with therapeutic activity; map biosynthetic pathways; and reveal new drug leads from plants, microbes, marine organisms, and human-associated microbiota. In this Special Issue, we aim to highlight recent advances in metabolomics-driven discovery, characterization, and application of natural products in drug development. We welcome the submission of studies that explore innovative analytical strategies; bioactivity-guided metabolomics; in silico metabolite prediction; metabolic pathway engineering; translational research; and the integration of metabolomics with pharmacology, toxicology, or systems biology.
By gathering cutting-edge contributions from across natural products research, in this Special Issue, we seek to advance our understanding of how metabolomics can reveal new therapeutic opportunities and accelerate the development of safer and more effective drugs.
Dr. Jeysson Sanchez-Suarez
Dr. Jennyfer Andrea Aldana Mejía
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolomics
- natural products
- drug discovery
- bioactive compounds
- computational metabolism
- pharmacology
- secondary metabolites
- therapeutic development
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