Pharmacology and Drug Metabolism
A section of Metabolites (ISSN 2218-1989).
Section Information
This section of Metabolites is focused on the change in and/or occurrence of small molecule metabolites in in vitro and in vivo systems triggered by drugs and other xenobiotics. This ranges from classic metabolism studied in new compounds to new and emerging tools as well as toxicometabolomics studies, which investigate the fate of the foreign compounds as well as changes in endogenous molecules.
The section “Pharmacology and Drug Metabolism“ in Metabolites is focused on but not limited to:
- Toxicometabolomics (e.g., metabolism of xenobiotics besides answering related metabolomics questions);
- Biomarkers of xenobiotics exposure (e.g., metabolomics to allow for tracing an intake);
- Detailed characterization of xenobiotics metabolism in biofluids and tissues;
- Effect of endogenous microorganisms on biotransformation (e.g., influence of human microbiome on drug metabolism;
- Fate of xenobiotics in wastewater (e.g., impact of microorganisms on survival rate);
- Emerging tools in metabolomics and applied mass spectrometry (e.g., in drug metabolism);
- Drug–drug interactions or drug–food interactions on the metabolism of drugs and, in consequence, on therapeutic management;
- Adverse drug reactions in polypharmacy patients and related management (e.g., PGx-based guiding);
- New developments in toxicokinetics/pharmacokinetics;
- Metabolism and toxicity of compounds released from packaging materials (toxicokinetics and biomonitoring).
Editorial Board
Topical Advisory Panel
Special Issues
Following special issues within this section are currently open for submissions:
- Drug Metabolism and New Drug Development for Cancers (Deadline: 31 August 2025)
- Secondary Metabolites and Their Activities: From the Identification to the Biological Investigation (Deadline: 31 August 2025)
- New Trends in Drug Pharmacokinetics and Metabolism Research (Deadline: 31 August 2025)
- Metabolite Profiling of Novel Psychoactive Substances (Deadline: 30 September 2025)
- Exploring and Expanding Horizons in Secondary Metabolites: Biosynthesis, Identification, Regulation and Biological Activity (Deadline: 30 November 2025)
- Pharmacodynamics and Innovative Therapeutic Strategies for Metabolic Disorders (Deadline: 28 February 2026)
- Drug Metabolism, Interactions and Toxicity: Advances in Metabolomics Approaches (Deadline: 28 February 2026)
- Applications of Mass Spectrometry in Elucidating Human Drug Metabolism: From the Preclinical Phase to Real-World Studies (Deadline: 1 March 2026)
- Advancements in Mass Spectrometry Techniques for Metabolomic and Pharmaceutical Analysis (Deadline: 30 June 2026)