Metabolomic Fingerprinting: Challenges and Opportunities

Dear Colleagues,

We are organizing a Special Issue entitled “Metabolomic Fingerprinting: Challenges and Opportunities” for Metabolites (MDPI).

The holistic analysis and simultaneous study of a wide array of small endogenous molecules from biological systems is one of the greatest strengths of metabolomic fingerprinting. However, metabolomics-based studies continue to face significant analytical challenges, mainly due to endogenous compounds' vast chemical diversity and varying concentration ranges. These challenges require specialized and advanced analytical techniques, as no single method can reveal all the properties of metabolites. Techniques such as High-Resolution Mass Spectrometry (HRMS), Two-Dimensional Liquid Chromatography (2D-LC), Capillary Electrophoresis (CE), Gas Chromatography (GC), and Ion Mobility Spectrometry (IMS) have propelled the progress of metabolic coverage, facilitating the discovery of new biomarkers and the understanding of their physiological mechanisms. These technologies provide high sensitivity and separation capabilities but also require advanced optimization and data analysis strategies. Their use allows for a deeper exploration of complex biological samples, aiding in discovering new biomarkers and understanding biochemical processes that impact health and disease. This Special Issue aims to showcase the latest approaches and methodologies related to the application of cutting-edge technologies, emphasizing both the technical challenges and the potential opportunities they present for a more comprehensive understanding of the multifaceted metabolomic profiles of biological systems.

We welcome articles and reviews, among other papers, to this Special Issue.

We look forward to receiving your contributions.

Dr. Christina Virgiliou
Dr. Olga-Angeliki Begou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.