Metabolic Complication of Obesity and Diabetes

A Special Issue of Metabolites (ISSN 2218-1989) belonging to the section "Endocrinology and Clinical Metabolic Research".

Deadline for manuscript submissions: 20 March 2027 | Viewed by 1

Editors


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Guest Editor
Department of Pediatrics, University of Medicine and Pharmacy “Victor Babes”, 300040 Timisoara, Romania
Interests: pediatric endocrinology; childhood and adolescent obesity; in-sulin resistance and metabolic syndrome; diabetes mellitus; metabolic and inflammatory biomarkers; dyslipidemia and cardiometabolic risk; polycystic ovary syndrome; metabolic bone disorders; rare endocrine diseases; endocrine tumors

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Guest Editor
School of Biomedical Sciences, Ulster University, Coleraine BT52 1SA, UK
Interests: diabetes; obesity; insulin secretion; insulin resistance; pre-clinical models; incretin hormones; gut peptides; cognitive function
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Special Issue Information

Dear Colleagues,

Obesity and diabetes represent major global health challenges affecting both pediatric and adult populations and contributing to a broad spectrum of metabolic complications. Alterations in metabolites and metabolic pathways involved in glucose and lipid metabolism, insulin resistance, dyslipidemia, chronic low-grade inflammation, adipose tissue dysfunction, and oxidative stress play central roles in the development and progression of obesity- and diabetes-related comorbidities.

This Special Issue, entitled “Metabolic Complication of Obesity and Diabetes”, aims to provide an interdisciplinary platform for original research and comprehensive reviews addressing metabolic pathways, biomarkers, clinical phenotypes, and consequences of metabolic dysfunction across the lifespan. Particular attention will be given to metabolites and metabolic and inflammatory biomarkers with potential value for early detection, risk stratification, and prediction of metabolic complications.

Topics of interest include insulin resistance and metabolic syndrome; alterations in glucose and lipid metabolism; dyslipidemia and lipotoxicity; metabolic and hematological inflammatory biomarkers; adipose tissue dysfunction and chronic inflammation; oxidative stress; gut microbiota dysbiosis and microbiome-derived metabolites; metabolic dysfunction-associated steatotic liver disease; obstructive sleep apnea and associated metabolic dysfunction; obesity-associated reproductive and endocrine disorders, including polycystic ovary syndrome; cardiometabolic complications; and metabolic alterations associated with diabetes and its complications.

Studies involving children, adolescents, and adults are encouraged, including clinical and biochemical investigations as well as metabolomic, lipidomic, microbiome-related, and other omics approaches. Studies investigating novel metabolites and metabolic biomarkers; metabolic phenotypes and pathways; predictors of disease progression; and metabolic responses to lifestyle, nutritional, pharmacological, or other therapeutic interventions are particularly welcome. The ultimate goal is to improve our understanding of metabolic dysfunction and support more precise strategies for risk assessment, prevention, and individualized management of obesity- and diabetes-related metabolic complications.

Dr. Giorgiana Flavia Brad
Prof. Dr. Victor Gault
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obesity
  • diabetes mellitus
  • insulin resistance
  • metabolic syndrome
  • metabolic biomarkers
  • lipid metabolism
  • metabolic inflammation
  • oxidative stress
  • gut microbiota
  • metabolic dysfunction-associated steatotic liver disease (MASLD)

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Published Papers

This special issue is now open for submission.
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