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Ischemic Heart Disease during Acute Exacerbations of COPD

1
Department of Pulmonary Medicine, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, Spain
2
Department of Cardiology, University Hospital Puerta de Hierro, Majadahonda, 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
Med. Sci. 2018, 6(4), 83; https://doi.org/10.3390/medsci6040083
Received: 3 July 2018 / Revised: 10 September 2018 / Accepted: 20 September 2018 / Published: 25 September 2018
(This article belongs to the Special Issue COPD Exacerbations)
Patients with chronic obstructive pulmonary disease (COPD) have a higher risk of acute cardiovascular events, and around 30% die from cardiovascular diseases. Recent data suggest an increased risk of myocardial infarction in the following days of a severe exacerbation of COPD. Disruption in the balance during the exacerbation with tachycardia, increased inflammation and systemic oxidative stress as well as some other factors may confer an increased risk of subsequent cardiovascular events. A number of investigations may be useful to an early diagnosis, including electrocardiography, imaging techniques and blood test for biomarkers. Some drugs that have changed prognosis in the cardiovascular setting such as cardioselective beta-blockers may be underused in patients with COPD despite its demonstrated benefits. This review focuses on several aspects of exacerbation of COPD and cardiovascular events including epidemiology, possible mechanism, diagnosis and treatment. View Full-Text
Keywords: chronic obstructive pulmonary disease; cardiovascular; myocardial infarction; exacerbation; treatment; beta-blockers chronic obstructive pulmonary disease; cardiovascular; myocardial infarction; exacerbation; treatment; beta-blockers
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Malo de Molina, R.; Aguado, S.; Arellano, C.; Valle, M.; Ussetti, P. Ischemic Heart Disease during Acute Exacerbations of COPD. Med. Sci. 2018, 6, 83.

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