Advances in Technology and Treatment in Thyroid Surgery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 3431

Special Issue Editors


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Guest Editor
Department of Otolaryngology-Head and Neck Surgery, Division of Endocrine Head and Neck Surgery, Johns Hopkins University, Bethesda, MD, USA
Interests: voice outcomes; swallow outcomes; thyroid surgery; laryngeal function

E-Mail Website
Guest Editor
Department of Otolaryngology-Head and Neck Surgery, Division of Endocrine Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA
Interests: thyroid surgery; scarless thyroid surgery; radiofrequency ablation; thyroid cancer

Special Issue Information

Dear Colleagues,

The advancements that have been made in thyroid surgery within the past decade have created opportunities and demonstrated improvement in the quality of endocrine surgical care for our patients. Thyroid surgery has become more than the operation itself; it has come to include a thoughtful and directed perioperative treatment planning, as well as transformed the operative management for our patients. Surgical techniques now include scarless thyroid surgery as well as radiofrequency ablation of thyroid nodules instead of excision of entire thyroid tissue. The aim and scope of this Special Issue is to explore these advances in more depth as well as to detail the research that has gone into the development and growth of some of these techniques and technologies. We will explore technologies such as in-office ultrasonography and describe how this feasible imaging modality and associated procedures have become a mainstay in the review of anatomy, operative planning and informed decision making when it comes to thyroid surgery. Other adjunct technologies such as intraoperative nerve monitoring continue to advance with new cutting-edge research and inform our ability to prevent neural injury. Finally, in a new trajectory, we will discuss artificial intelligence and its capabilities in thyroid surgery.

This Special Issue includes the following topics for discussion, all of which we hope will inform and educate the reader and the thyroid surgical enthusiast on the future of thyroid surgery.

Dr. Vaninder K. Dhillon
Dr. Jonathon O. Russell
Guest Editors

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Keywords

  • in-office ultrasound
  • molecular testing
  • thyroid nodules
  • radiofrequency ablation
  • scarless thyroid surgery
  • artifical intelligence
  • intraoperative nerve monitoring

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Published Papers (1 paper)

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Review

23 pages, 498 KiB  
Review
Can We Predict Differentiated Thyroid Cancer Behavior? Role of Genetic and Molecular Markers
by Rita Niciporuka, Jurijs Nazarovs, Arturs Ozolins, Zenons Narbuts, Edvins Miklasevics and Janis Gardovskis
Medicina 2021, 57(10), 1131; https://doi.org/10.3390/medicina57101131 - 19 Oct 2021
Cited by 8 | Viewed by 3044
Abstract
Thyroid cancer is ranked in ninth place among all the newly diagnosed cancer cases in 2020. Differentiated thyroid cancer behavior can vary from indolent to extremely aggressive. Currently, predictions of cancer prognosis are mainly based on clinicopathological features, which are direct consequences of [...] Read more.
Thyroid cancer is ranked in ninth place among all the newly diagnosed cancer cases in 2020. Differentiated thyroid cancer behavior can vary from indolent to extremely aggressive. Currently, predictions of cancer prognosis are mainly based on clinicopathological features, which are direct consequences of cell and tissue microenvironment alterations. These alterations include genetic changes, cell cycle disorders, estrogen receptor expression abnormalities, enhanced epithelial-mesenchymal transition, extracellular matrix degradation, increased hypoxia, and consecutive neovascularization. All these processes are represented by specific genetic and molecular markers, which can further predict thyroid cancer development, progression, and prognosis. In conclusion, evaluation of cancer genetic and molecular patterns, in addition to clinicopathological features, can contribute to the identification of patients with a potentially worse prognosis. It is essential since it plays a crucial role in decision-making regarding initial surgery, postoperative treatment, and follow-up. To date, there is a large diversity in methodologies used in different studies, frequently leading to contradictory results. To evaluate the true significance of predictive markers, more comparable studies should be conducted. Full article
(This article belongs to the Special Issue Advances in Technology and Treatment in Thyroid Surgery)
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