Impact of Multi-Morbidity and Polypharmacy on Health Outcomes in Older Age

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Geriatrics/Aging".

Deadline for manuscript submissions: closed (31 October 2019) | Viewed by 5508

Special Issue Editor


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Guest Editor
Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, AB25 2ZD, UK
Interests: health services research; dementia; cardiovascular diseases; healthy ageing
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Special Issue Information

Dear Colleagues,

Aging is associated with the accumulation of multiple chronic diseases and increased risk of varying degrees of physical, cognitive, and emotional impairment. Consequently, this multi-morbidity has led to polypharmacy, which is usually defined as taking five or more medications. Polypharmacy is associated with increased risk of drug interactions, adverse effects, and other side effects, such as falls in older people. Polypharmacy may also increase the risk of cognitive and physical impairment and frailty in elderly people, independent of other risk factors. Decline in cognitive, social, and emotional function frequently coexists with physical dysfunction in late life, and there may be common pathological pathways.

In this Special Issue, we are interested in receiving articles that will help us to better understand the impact of multi-morbidity and polypharmacy on physical, mental, and social outcomes, which are related to health and social care in older age. We welcome a wide range of research papers that provide epidemiological observations, trial evidence, and mechanistic links.

Prof. Dr. Phyo Myint
Guest Editor

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Keywords

  • Multi-Morbidity
  • Polypharmacy
  • Older Age

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Published Papers (1 paper)

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Research

6 pages, 260 KiB  
Communication
The Scottish Intercollegiate Guidelines Network (SIGN) 157: Guidelines on Risk Reduction and Management of Delirium
by Roy L. Soiza and Phyo K. Myint
Medicina 2019, 55(8), 491; https://doi.org/10.3390/medicina55080491 - 15 Aug 2019
Cited by 25 | Viewed by 5037
Abstract
The Scottish Intercollegiate Guidelines Network (SIGN) guideline on delirium is a major advance on existing guidelines on this condition. This is particularly important given the evidence it is frequently under-diagnosed and inadequately managed despite being common and frequently associated with significant patient and [...] Read more.
The Scottish Intercollegiate Guidelines Network (SIGN) guideline on delirium is a major advance on existing guidelines on this condition. This is particularly important given the evidence it is frequently under-diagnosed and inadequately managed despite being common and frequently associated with significant patient and carer distress and poor outcomes. The guidelines recommend using the 4A’s test to help detect delirium. A bundle of mostly non-pharmacological therapies minimise the risk of developing delirium and can help those who develop the condition. The importance of medical optimisation by an experienced professional in those at risk of delirium is highlighted with new recommendations for people in intensive care and surgical settings. There is guidance on follow-up of people with delirium, which should become routine. This commentary piece focusses on areas with the greatest potential to improve the experience and outcomes of those with delirium, and briefly discusses areas of ongoing uncertainty. Full article
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