Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
3.6
2.6
Journals
Medicina
Special Issues
Biology of Obstructive Sleep Apnea and Cancer
share announcement

Biology of Obstructive Sleep Apnea and Cancer

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Translational Medicine".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1002

Special Issue Editors

Dr. Tilman Huppertz

E-Mail Website
Guest Editor
Sleep Medicine Center, Department of Otolaryngology, University Medical Center, Johannes Gutenberg University Mainz, 55131 Mainz, Germany
Interests: head and neck cancer; sleep; sleep apnea; olfaction; biologicals; allergy
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Haralampos Gouveris

E-Mail Website
Guest Editor
Sleep Medicine Center, Department of Otorhinolaryngology, Medical Center of the University of Mainz, 55131 Mainz, Germany
Interests: hypoxia; taste; olfaction; hearing; head and neck; sleep; sleep apnea; clinical
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Obstructive sleep apnea (OSA) is a highly prevalent disease affecting almost 50% of the male and almost 25% of the female adult population in Western Europe, with similar figures seen worldwide. Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 according to the WHO. A connection between these two entities has been postulated for years, with the literature on an association between obstructive sleep apnea (OSA) and cancer gaining momentum in the last few years. More and more malignant entities are being associated with OSA in small cohort or case control studies as well as in large population-based studies. Future studies should further corroborate these findings, focus on effects of treatment of OSA on cancer morbidity as well as mortality, and give insights into underlying molecular mechanisms of the association.

For this Special Issue, “Biology of Obstructive Sleep Apnea and Cancer”, we invite submissions of original articles and review articles to cover recent basic and translational research  involving the study of possible links between various cancer entities and OSA. The aim is to highlight and promote awareness on this matter in the scientific community and hence accelerate relevant research.

You may choose our Joint Special Issue in Biology.

Dr. Tilman Huppertz
Prof. Dr. Haralampos Gouveris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obstructive sleep apnea
  • hypopnea
  • hypoxia
  • cancer
  • tumor
  • carcinoma
  • lymphoma
  • quality of life
  • sleep quality
  • metabolism
  • cardiorespiratory home sleep apnea testing
  • polysomnography
  • smoking and alcohol consumption

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

13 pages, 2299 KiB  
Article
Prevalence of Obstructive Sleep Apnea in Head and Neck Squamous Cell Carcinoma Patients before and after Treatment
by Olaf Gil, Benjamin Fenske, Thomas Bremert, Marcus Vollmer, Christian Scharf, Chia-Jung Busch and Markus Blaurock
Medicina 2024, 60(2), 310; https://doi.org/10.3390/medicina60020310 - 11 Feb 2024
Viewed by 854
Abstract
Background and Objectives: Obstructive sleep apnea (OSA) is common not only in the general population but even more so in patients with tumors of the head and neck region. Untreated, it leads to reduced quality of life, increased daytime sleepiness, and other [...] Read more.
Background and Objectives: Obstructive sleep apnea (OSA) is common not only in the general population but even more so in patients with tumors of the head and neck region. Untreated, it leads to reduced quality of life, increased daytime sleepiness, and other comorbidities. The aim of this study was to determine the difference in the occurrence of OSA in the patient population with head and neck tumors compared with the general population as represented by the Trend cohort of the Study of Health in Pomerania (SHIP), and to assess the influence of tumor treatment. Materials and Methods: Between July 2018 and December 2021, preoperative polysomnography was conducted in 47 patients with histologically confirmed squamous cell carcinoma in the oropharynx, hypopharynx, or larynx. A follow-up polysomnography was performed in 23 patients 2–11 months after completing treatment. The collected data were correlated with tumor treatment and tumor size. Results: Of the included patients, 43 were male and 4 were female. Age ranged from 54 to 90 years. The pretherapeutic measurement found no significant difference in the prevalence of a pathologically elevated apnea–hypopnea index (AHI) in our patients compared with the SHIP Trend cohort. In the follow-up measurement after completion of treartment, a significant deterioration in AHI was observed. Initially, 70% of patients had an AHI > 5; after therapy, this increased to 87% (p = 0.008). The effect was particularly pronounced in the group of patients with advanced tumor stages who had received primary chemoradiation. Conclusions: OSA is a relevant condition in patients with head and neck cancer. Tumor treatment can lead to an increased occurrence of sleep-related breathing disorders, especially in patients with advanced tumor stages undergoing primary chemoradiation. Additional studies are necessary to better understand the exact mechanism involved. Full article
(This article belongs to the Special Issue Biology of Obstructive Sleep Apnea and Cancer)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop