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Medicina
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Clinical Advances in Surgical Treatment of Obesity
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Clinical Advances in Surgical Treatment of Obesity

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Surgery".

Deadline for manuscript submissions: closed (25 June 2024) | Viewed by 2155

Special Issue Editors

Prof. Dr. Till Hasenberg

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Guest Editor
1. Department of General, Abdominal Surgery and Coloproctology, Helios St. Elisabeth Klinik, Oberhausen, Germany
2. Helios Obesity Center West, Helios St. Elisabeth Hospital Oberhausen, Oberhausen, Germany
3. Helios University Hospital Wuppertal, Wuppertal, Germany
4. Faculty of Health, University of Witten/Herdecke, Witten, Germany
Interests: bariatric surgery; metabolic surgery; obesity
Special Issues, Collections and Topics in MDPI journals
Dr. Sjaak Pouwels

E-Mail
Guest Editor
1. Department of General, Abdominal Surgery and Coloproctology, Helios St. Elisabeth Klinik, Oberhausen, Germany
2. Helios Obesity Center West, Helios St. Elisabeth Hospital Oberhausen, Oberhausen, Germany
3. Faculty of Health, University of Witten/Herdecke, Witten, Germany
Interests: intensive care medicine; bariatric surgery; oncological surgery; logistics; perioperative optimalisation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The treatment of obesity is evolving rapidly and medical specialists have a lot of tools at their diposal to treat obesity. Nowadays, bariatric and metabolic surgery plays a pivotal role in treating patients with obesity and related comorbidities. New treatments have been developed in both surgical and medical fields, such as newer surgical techniques, anti-obesity medication and endoscopic procedures. The aim of this Special Issue is to provide a comprehensive overview of the advances in the surgical and non-surgical treatment of obesity, with particular interest in the use of innovative surgical techniques and treatment concepts. Therefore, researchers in the field of obesity medicine are encouraged to submit their findings as original articles or reviews to this Special Issue.

You may choose our Joint Special Issue in JCM.

Prof. Dr. Till Hasenberg
Dr. Sjaak Pouwels
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bariatric surgery
  • metabolic surgery
  • anti-obesity medication
  • surgical innovations
  • innovative treatment concepts
  • comorbidity resolution

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Published Papers (1 paper)

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Research

11 pages, 868 KiB  
Article
Short-Term Changes in TNF-Alpha, IL-6 and Adiponectin Following Bariatric Surgery in Caucasian Obese Adults: An Observational Case–Control Study
by Razvan-Marius Ion, Adina Hutanu, Daniela Tatiana Sala, Mircea Gabriel Muresan, Stefania R. Fodor, Septimiu Voidazan, Gabriela Beresescu and Radu Mircea Neagoe
Medicina 2024, 60(11), 1789; https://doi.org/10.3390/medicina60111789 - 1 Nov 2024
Cited by 1 | Viewed by 1760
Abstract
Background and Objectives: Overweight and obesity are well-known conditions that negatively impact the health and lifestyle of an individual. Bariatric surgery is one of the most efficient weight loss techniques. Besides the main effect on the bodyweight, improvement in the levels of inflammatory [...] Read more.
Background and Objectives: Overweight and obesity are well-known conditions that negatively impact the health and lifestyle of an individual. Bariatric surgery is one of the most efficient weight loss techniques. Besides the main effect on the bodyweight, improvement in the levels of inflammatory biomarkers, such as interleukin 6 (IL-6), tumor necrosis factor alpha (TNFalfa), and others, has been observed. The purpose of this study was to establish the correlations between obesity-linked chronic systemic inflammation (estimated with inflammatory cytokine levels) and the weight loss process after metabolic surgery. Materials and Methods: An observational cohort study included two categories: the patients with obesity–bariatric group and the patients without obesity–control group. The study was performed between 1 February 2021 and 1 March 2023. Baseline characteristics, anthropometrics, biochemical assessment and inflammatory biomarkers were measured both before surgery and one year after the procedure, in the case of the bariatric group. The control group was assessed in the same period as the pre-surgery bariatric group. The bariatric group underwent two types of bariatric procedures: the majority underwent laparoscopic sleeve gastrectomy whereas a select few underwent one anastomosis laparoscopic gastric bypass. Results: We performed a prospective study comprising 55 Caucasian patients—from which 33 patients had morbid obesity, a mean age of 41.76 ± 10.78 and a mean BMI of 43.34± 7.51 kg/m2. The preoperative levels of IL-6 were positively correlated with waist circumference (r = 0.354, p = 0.043), weight (r = 0.549, p = 0.001) and BMI (r = 0.520, p = 0.002). After applying the Kruskal–Wallis test and Dunn’s test, significant differences for IL-6 (p = 0.010) and adiponectin (p = 0.024) were obtained for values recorded pre- and post-surgery. No correlation was found between adiponectin, IL-6, TNF- α levels and anthropometric indices after surgery. Our study showed that bariatric surgery significantly changes the values of inflammatory cytokines one year after surgery. Nevertheless, we did not find significant correlations between the baseline values of these inflammatory markers and the weight loss process after surgery at a short-term (one-year) follow-up. Conclusions: Our study demonstrated that bariatric surgery significantly changes the level of inflammatory cytokines one year after operation. We demonstrate that preoperative levels of IL-6 are positively correlated with age, WC, and BMI. Full article
(This article belongs to the Special Issue Clinical Advances in Surgical Treatment of Obesity)
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