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Medicina
Special Issues
Effects of Abdominal Hysterectomy on Gynecological Patients: 2nd Edition
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Effects of Abdominal Hysterectomy on Gynecological Patients: 2nd Edition

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Obstetrics and Gynecology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 1583

Special Issue Editor

Dr. Stefano Cianci

E-Mail Website
Guest Editor
Department of Obstetrics and Gynecology, University of Messina, 98122 Messina, Italy
Interests: hysterectomy; ovarian cancer; gynecologic oncology; gynaecological surgery; laparoscopic surgery; ovary; cancer prevention; cancer care facilities
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to invite you to contribute to the Special Issue entitled “Effects of Abdominal Hysterectomy on Gynecological Patients: 2nd Edition”. This is our new volume; we published eight papers in the first volume. For more details, please visit

https://www.mdpi.com/journal/medicina/special_issues/5VZ0O939Y7

Hysterectomies are among the most frequently performed surgical procedures worldwide. A hysterectomy can be performed for benign disease, oncology, or hemodynamic instability in emergency cases of metrorrhagia. Over the years, several concerns have arisen about patients’ quality of life, pelvic stability, and vascular, ureteral, and bowel complications after hysterectomy. However, a hysterectomy remains a necessary treatment in cases of gynecological oncological pathology or a life-saving treatment in emergency cases.

In this Special Issue, we aim to review the role of hysterectomies in various gynecological diseases. Furthermore, different laparotomic, laparoscopic, and robotic surgical approaches will be reviewed, and the latest technologies for performing a hysterectomy will be investigated.

We are inviting submissions of original articles, reviews, systematic reviews, case reports, and meta-analyses for this Special Issue.

Dr. Stefano Cianci
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gynecologic disease
  • hysterectomy
  • surgery
  • endometrial cancer
  • ovarian cancer

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Related Special Issue

Published Papers (1 paper)

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Review

11 pages, 292 KiB  
Review
Fertility-Sparing Treatments in Endometrial Cancer: A Comprehensive Review on Efficacy, Oncological Outcomes, and Reproductive Potential
by Carlo Ronsini, Paola Romeo, Giada Andreoli, Vittorio Palmara, Marco Palumbo, Giuseppe Caruso, Pasquale De Franciscis, Giuseppe Vizzielli, Stefano Restaino, Vito Chiantera and Stefano Cianci
Medicina 2025, 61(3), 471; https://doi.org/10.3390/medicina61030471 - 7 Mar 2025
Viewed by 1116
Abstract
Endometrial cancer (EC) affects 3–14% of women under 40 who wish to preserve their fertility. The standard treatment for EC is a hysterectomy with salpingo-oophorectomy. However, for those desiring fertility preservation, oral progestogens such as medroxy-progesterone acetate (MPA) or megestrol acetate (MA) are [...] Read more.
Endometrial cancer (EC) affects 3–14% of women under 40 who wish to preserve their fertility. The standard treatment for EC is a hysterectomy with salpingo-oophorectomy. However, for those desiring fertility preservation, oral progestogens such as medroxy-progesterone acetate (MPA) or megestrol acetate (MA) are the most common therapies in Fertility-Sparing Treatment (FST). Other treatments include gonadotropin-releasing hormone agonist (GnRHa), levonorgestrel-releasing intrauterine system (LNG-IUS), and metformin plus progestin. This comprehensive review evaluates the best FST options for women with reproductive potential. PubMed, EMBASE, and Scopus were searched in June 2023 using specific keywords. Studies included in the review focused on patients with EC undergoing FST, with outcomes such as complete response rate (CRR), recurrence rate (RR), pregnancy rate (PR), and live birth rate. Eighteen studies met the inclusion criteria, involving 23,976 patients. In only-oral progestin trials, CRR ranged from 18% to 100%; RR ranged from 0% to 81.8%; Death Rate ranged from 0% to 3.6%. In studies combining oral progestin with LNG-IUS, CRR ranged from 55% to 87.5%; RR ranged from 0% to 41.7%; Death Rate was 0%. Most patients with Stage IA EC received MPA or MA. Fertility-related outcomes were reported in 15 studies. PR ranged from 4 to 44 patients in trials involving only oral progestins. When combining oral progestin with LNG-IUS, PR ranged from 1 to 46 patients. Progestin therapy, including oral MPA and MA, is considered safe and effective, with limited evidence supporting the use of LNG-IUS. Full article
(This article belongs to the Special Issue Effects of Abdominal Hysterectomy on Gynecological Patients: 2nd Edition)
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