Emerging Biomarkers and Therapeutic Approaches in Neurovascular Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 March 2025) | Viewed by 569
Special Issue Editors
Interests: intracranial aneurysm; giant aneurysm; intracranial bypass; aneurysmal subarachnoid haemorrhage; delayed cerebral ischemia; computational fluid dynamics; neurovascular compression syndromes; biomarkers
Interests: neurosurgery; neuro-oncology; brain tumors; genetic predispostition to cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurovascular disease encompasses a wide range of conditions, including stroke (both ischaemic and haemorrhagic), intracerebral haemorrhages, intracranial aneurysms, arteriovenous malformations, cavernous malformations and dural arteriovenous fistulae (DAVFs, e.g., those formed in the course of venous sinus thrombosis). These conditions can lead to potentially life-threatening bleeding and neurological complications.
Despite our growing knowledge base; the advances in treatment modalities, whether conservative, endovascular or surgical; and the increasing availability of state-of-the-art equipment in vascular laboratories and operating theatres, much remains to be clarified. For example, which intracranial aneurysms are most prone to rupture, and when, and what are the optimal treatment approaches? Should these aneurysms be treated surgically or endovascularly, and in which settings? Of those that do rupture, which patients will develop cerebral vasospasm and which will suffer delayed cerebral ischaemia (DCI)? Furthermore, which clinical, radiological, serum/plasma or CSF biomarkers can be used for the early detection of these complications, and how can this information be utilized for effective prevention?
Consider an intracerebral haemorrhage: when should it be managed conservatively and when is surgical intervention required? Should its treatment involve a decompressive craniectomy, the surgical evacuation of the bleed, or modern minimally invasive techniques such as the Artemis system? Are there biomarkers that can guide the selection of these different treatment strategies for patients, and which of these can help predict patient outcomes?
The exact pathogenesis of DAVFs remains elusive. What is the risk of bleeding from these fistulas, and what is the most effective treatment approach? Furthermore, how should patients be monitored after treatment to ensure long-term vigilance and detect potential recurrences or complications?
Many issues surrounding neurovascular disease have not been addressed here. In fact, there are numerous smaller entities and conditions that could not be included in this summary of the research topic. Even for the above questions, the answers remain incomplete, highlighting how much work remains to be done in this field. With this in mind, we encourage active participation in the development of a series of studies under the umbrella title “Emerging Biomarkers and Therapeutic Approaches in Neurovascular Diseases”. We invite the submission of original research articles and reviews that address these important questions.
Dr. Karol Wiśniewski
Dr. Bartosz Szmyd
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- intracranial aneurysm
- giant aneurysm
- intracranial bypass
- aneurysmal subarachnoid haemorrhage
- delayed cerebral ischemia
- computational fluid dynamics
- neurovascular compression syndromes
- biomarkers
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
