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Medicina
Special Issues
Advances in Knee Surgery: From Diagnosis to Recovery
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Advances in Knee Surgery: From Diagnosis to Recovery

A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 15 June 2026 | Viewed by 723

Special Issue Editors

Prof. Dr. Yong In

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea
Interests: knee osteoarthritis; cartilage regeneration; arthroplasty implant design
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. In Jun Koh

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 03312, Republic of Korea
Interests: total knee arthroplasty; knee osteoarthritis; cartilage regeneration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Following the great success of our first Special Issue, “Advances in Knee Surgery” (2022), which featured 24 outstanding papers, we are pleased to announce the launch of its second edition, “Advances in Knee Surgery: From Diagnosis to Recovery.” This Issue aims to highlight the most recent innovations and future directions in knee surgery.

In recent years, remarkable progress has been achieved in both surgical techniques and digital technologies, including computer-assisted and robotic systems, artificial intelligence-driven planning, and biologic augmentation. This Special Issue aims to showcase the latest advances across the full spectrum of knee surgery—from ligament, meniscus, and cartilage repair to osteotomy and arthroplasty—by integrating precision medicine, advanced  imaging, and data-driven approaches.

We invite submissions of original research articles and systematic reviews that explore evolving surgical strategies and emerging technologies shaping the future of personalized knee reconstruction.

Prof. Dr. Yong In
Prof. Dr. In Jun Koh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medicina is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee surgery
  • arthroplasty
  • osteotomy
  • cartilage regeneration
  • meniscus repair
  • ligament reconstruction
  • artificial intelligence
  • robotics

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Published Papers (2 papers)

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Research

12 pages, 5420 KB  
Article
Functional Differences in the Affected Limbs Between CPAK Type I and Type II Patients Undergoing Unilateral Total Knee Arthroplasty
by Ju Won Bae, Seung Ik Cho, Dhong Won Lee, Byung Sun Park, Yu Bin Lee, Wonjun Chang and Joon Kyu Lee
Medicina 2026, 62(2), 259; https://doi.org/10.3390/medicina62020259 - 26 Jan 2026
Abstract
Background and Objectives: This study compared functional performance, gait performance, and dynamic balance between Coronal Plane Alignment of the Knee (CPAK) Type I and Type II patients undergoing unilateral total knee arthroplasty (TKA). Materials and Methods: We included 162 consecutive patients scheduled for [...] Read more.
Background and Objectives: This study compared functional performance, gait performance, and dynamic balance between Coronal Plane Alignment of the Knee (CPAK) Type I and Type II patients undergoing unilateral total knee arthroplasty (TKA). Materials and Methods: We included 162 consecutive patients scheduled for unilateral TKA between January 2022 and August 2025. Patients were classified according to CPAK type; 42 were Type I and 33 were Type II. Preoperative assessments included demographic data, Korean Knee Score, and WOMAC. Functional performance was evaluated using the Timed Up and Go (TUG) test and the 4 m walk test. Isokinetic knee extensor and flexor strength (60°/s), hip abductor strength, and bilateral thigh circumferences measured 5 cm and 15 cm proximal to the patella were assessed. Dynamic balance asymmetry was evaluated using the POSTUROMED device. Inter-limb differences were calculated by comparing the operated and non-operated limbs. Results: No significant between-group differences were observed in clinical scores, knee extensor, or flexor strength deficits, hip abductor strength deficits, or thigh circumference differences. However, CPAK Type II patients demonstrated significantly better functional performance, with faster TUG (p = 0.014) and 4 m walk test times (p = 0.022). Dynamic balance outcomes were also significantly better in the Type II group (p = 0.042). Conclusions: Despite similar patient-reported clinical scores and muscle strength, patients with the CPAK Type II phenotype exhibited superior gait performance and dynamic balance compared with those with Type I following unilateral TKA. Full article
(This article belongs to the Special Issue Advances in Knee Surgery: From Diagnosis to Recovery)
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12 pages, 8211 KB  
Article
Novel Visual Grade and Hounsfield Unit Predict Adequate Bone Strength for Cementless Total Knee Arthroplasty
by Dong Hwan Lee, Dai-Soon Kwak, Sheen-Woo Lee, Yong Deok Kim, Nicole Cho and In Jun Koh
Medicina 2025, 61(11), 2018; https://doi.org/10.3390/medicina61112018 - 12 Nov 2025
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Abstract
Background and Objectives: The use of cementless total knee arthroplasty (TKA) is increasing, but established methods for assessing bone quality to prevent early failure remain undefined. Current preoperative assessments using central bone mineral density (BMD) do not accurately reflect peripheral bone quality, [...] Read more.
Background and Objectives: The use of cementless total knee arthroplasty (TKA) is increasing, but established methods for assessing bone quality to prevent early failure remain undefined. Current preoperative assessments using central bone mineral density (BMD) do not accurately reflect peripheral bone quality, and intraoperative evaluation is subjective. This study aimed to establish objective assessment methods by analyzing the correlations between a novel visual grading system, CT Hounsfield units (HU), and actual bone strength. Materials and Methods: This prospective study included 131 patients undergoing posterior-stabilized TKA. We developed a novel visual grading system (Excellent, Good, Fair, Poor) based on femoral cutting surface characteristics. CT HUs were measured preoperatively by an assisting surgeon in the box bone area. Femoral box specimens underwent indentation testing to determine their actual bone strength. Minimum Required Strength (MRS) was defined at 2.5-fold the patient’s body weight, and Estimated Withstanding Strength (EWS) was determined by scaling first failure load using area ratios. Patients were classified as “cementless suitable” (EWS > MRS) or “cemented mandatory” (EWS < MRS). Correlations were assessed using Spearman’s rank correlation for visual grade and Pearson correlation for Hounsfield units. ROC curve analysis determined diagnostic accuracy. Results: Visual grade exhibited an exceptionally robust relationship to bone strength (Spearman ρ = 0.903, p < 0.01), whereas HU showed substantial correlation (Pearson r = 0.660, p < 0.01, R2 = 0.435). Visual grading achieved excellent diagnostic accuracy (AUC = 0.974, sensitivity 95.1%, specificity 95.9%) using “Good” grade as cutoff. HU demonstrated AUC of 0.938 with 92.7% sensitivity and 81.6% specificity at a cutoff value of 65.2. Conclusions: Our novel visual grading system and CT HU demonstrated excellent correlations with actual distal femoral bone strength and outstanding diagnostic performance for identifying cementless TKA candidates. Unlike traditional subjective intraoperative assessments such as the “thumb test”, this system provides objective visual criteria directly correlated with actual bone strength. Preoperative HU screening with intraoperative visual grading can help prevent early failure. Full article
(This article belongs to the Special Issue Advances in Knee Surgery: From Diagnosis to Recovery)
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