materials-logo

Journal Browser

Journal Browser

Oral and Maxillofacial Regenerative Materials

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (10 May 2022) | Viewed by 3556

Special Issue Editors


E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Shimane University, Shimane, Japan
Interests: oral and maxillofacial surgery; maxillofacial regeneration; biomaterial; maxillofacial reconstruction
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan
Interests: oral and maxillofacial surgery; Artificial Intelligence; orthognathic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The treatment goal of oral and maxillofacial reconstructive surgery following oral–maxillofacial resection and/or defects due to various congenital or acquired lesions such as tumors, neoplasm, trauma, infection or anomaly is to reconstruct/replace normal and healthy oral and maxillofacial bone and soft-tissue volume and structures. These reconstructed tissues should be functionally stable and well vascularized to undergo normal homeostasis. Regenerative technology is at the forefront of our medical and dental research. Polymer-based regenerative biomaterials such as bioresorbable and biodegradable osteosynthetic fixation systems or boney reconstruction implant materials have recently been considered to be effective bone regenerative reconstruction systems that offer several advantages over conventional materials. Currently, four main types of reconstructive materials are available to clinicians for oral–maxillofacial regenerative application in oral and maxillofacial surgery: autologous bone, allogenic bone, xenogenic bone, and alloplastic bone. In addition, stem cells, bioactive agents, and growth factors are now being widely used to stimulate osteoinductive/osteoconductive regenerative properties of native bone and various biomaterials for active bone regeneration.

For this Special Issue, I would like to feature any original research articles from clinical studies as well as in vitro and in vivo studies, reviews, short reports, or opinion pieces from researchers interested in these research topics of “Oral and Maxillofacial Regenerative Materials”.

Prof. Dr. Takahiro Kanno
Dr. Shintaro Sukegawa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral and maxillofacial surgery
  • bone regeneration
  • biomaterial
  • stem cell
  • reconstructive surgery
  • dental material

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

32 pages, 10729 KiB  
Review
A Narrative Review of u-HA/PLLA, a Bioactive Resorbable Reconstruction Material: Applications in Oral and Maxillofacial Surgery
by Huy Xuan Ngo, Yunpeng Bai, Jingjing Sha, Shinji Ishizuka, Erina Toda, Rie Osako, Akira Kato, Reon Morioka, Mrunalini Ramanathan, Hiroto Tatsumi, Tatsuo Okui and Takahiro Kanno
Materials 2022, 15(1), 150; https://doi.org/10.3390/ma15010150 - 26 Dec 2021
Cited by 15 | Viewed by 3730
Abstract
The advent of bioresorbable materials to overcome limitations and replace traditional bone-reconstruction titanium-plate systems for bone fixation, thus achieving greater efficiency and safety in medical and dental applications, has ushered in a new era in biomaterial development. Because of its bioactive osteoconductive ability [...] Read more.
The advent of bioresorbable materials to overcome limitations and replace traditional bone-reconstruction titanium-plate systems for bone fixation, thus achieving greater efficiency and safety in medical and dental applications, has ushered in a new era in biomaterial development. Because of its bioactive osteoconductive ability and biocompatibility, the forged composite of uncalcined/unsintered hydroxyapatite and poly L-lactic acid (u-HA/PLLA) has attracted considerable interest from researchers in bone tissue engineering, as well as from clinicians, particularly for applications in maxillofacial reconstructive surgery. Thus, various in vitro studies, in vivo studies, and clinical trials have been conducted to investigate the feasibility and weaknesses of this biomaterial in oral and maxillofacial surgery. Various technical improvements have been proposed to optimize its advantages and limit its disadvantages. This narrative review presents an up-to-date, comprehensive review of u-HA/PLLA, a bioactive osteoconductive and bioresorbable bone-reconstruction and -fixation material, in the context of oral and maxillofacial surgery, notably maxillofacial trauma, orthognathic surgery, and maxillofacial reconstruction. It simultaneously introduces new trends in the development of bioresorbable materials that could used in this field. Various studies have shown the superiority of u-HA/PLLA, a third-generation bioresorbable biomaterial with high mechanical strength, biocompatibility, and bioactive osteoconductivity, compared to other bioresorbable materials. Future developments may focus on controlling its bioactivity and biodegradation rate and enhancing its mechanical strength. Full article
(This article belongs to the Special Issue Oral and Maxillofacial Regenerative Materials)
Show Figures

Figure 1

Back to TopTop