Advanced Biomaterial Characterization Techniques: Spectroscopy and Electron Microscopy Analysis

Dear Colleagues,

Rapid advances in biomaterial research have resulted in a high demand for equally advanced analytical tools to understand structure–property relationships, biological interactions, and long-term material performance. Among these tools, spectroscopy and electron microscopy techniques play central roles by enabling the high-resolution, multidimensional, and often nanoscale characterization required for modern biomaterial development.

This Special Issue aims to highlight recent progress, emerging methodologies, and innovative applications of spectroscopy and electron microscopy for the study of biomaterials. Contributions that introduce new analytical workflows; provide deeper mechanistic insights; or demonstrate how state-of-the-art characterization techniques are especially welcome to guide the design of next-generation biomaterials.

Topics of interest include, but are not limited to the following:

• Spectroscopic techniques for biomaterials characterization (FTIR, Raman, NMR, XPS, UV-Vis, EELS, etc.).
• Electron microscopy methods (SEM, TEM, Cryo-TEM, STEM, FIB-SEM, and tomography) for structural and morphological analysis.
• Correlative microscopy and multimodal imaging approaches.
• Surface chemistry, topography, and interface analysis.
• In situ, operando, and real-time characterization of biomaterial behavior.
• Structural characterization of polymers, hydrogels, composites, bioactive ceramics, metals, and nanomaterials.
• Imaging and spectroscopic studies of cell–material and tissue–material interactions.
• Quantitative image analysis, machine learning, and automation in biomaterials characterization.
• Advanced sample preparation methods for biological and hybrid materials.
• Case studies linking characterization results to material design, performance, or clinical translation.

Dr. Inga Morkvenaite-Vilkonciene
Guest Editor

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