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The Application of Nano-Modified Titanium
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The Application of Nano-Modified Titanium

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 5226

Special Issue Editor

Prof. Dr. Joji Okazaki

E-Mail Website
Guest Editor
Department of Removable Prosthodontics and Occlusion, Osaka Dental University, 1 Chome-4-4 Makinohonmachi, Hirakata, Osaka 573-1144, Japan
Interests: dental materials; dental implants; surface analysis; in vivo analysis; denture materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I am pleased to announce the Special Issue of the MDPI journal Materials devoted to the “The Application of Nano-Modified Titanium”.

A lot of studies in implant research has evaluated the modification of the surface of the implant material at the nano-meter level. Techniques that provide an increased surface area and finer surface roughness may yield better tissue-titanium mechanical interlocking. However, more importantly, such nanoscopic features are also believed to directly affect osteogenic cell behavior around implant fixtures possessing non-conventional surfaces, creating a biomimetic relationship between alloplastic surfaces and host tissues through the replication of the natural cellular environment at the nanometer level.

Previous research on the interface between nanostructured materials and tissues is not sufficient and further studies are required. We also need a lot of research reports, including studies using this device, such as experiments using zirconia and peaks.

The topics of interest for this this Special Issue will include (but are not restricted to):

  • Nano materials (other than titanium)
  • Tissue engineering
  • Interface research
  • Materials processing and design
  • Biocompatibility

Prof. Joji Okazaki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nano structure
  • Application of nano materials
  • Characterization
  • Biocompatibility
  • Osseointegration
  • Antibacterial
  • Development of new materials using nanostructures

Published Papers (2 papers)

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Research

15 pages, 9333 KiB  
Article
Effects of UV Treatment on Ceria-Stabilized Zirconia/Alumina Nanocomposite (NANOZR)
by Satoshi Komasa, Seiji Takao, Yuanyuan Yang, Yuhao Zeng, Min Li, Sifan Yan, Honghao Zhang, Chisato Komasa, Yasuyuki Kobayashi, Hiroshi Nishizaki, Hisataka Nishida, Tetsuji Kusumoto and Joji Okazaki
Materials 2020, 13(12), 2772; https://doi.org/10.3390/ma13122772 - 18 Jun 2020
Cited by 4 | Viewed by 2255
Abstract
Nanostructured zirconia/alumina composite (NANOZR) has been explored as a suitable material for fabricating implants for patients with metal allergy. In this study, we examined the effect of UV treatment on the NANOZR surface. The experimental group was UV-treated NANOZR and the control group [...] Read more.
Nanostructured zirconia/alumina composite (NANOZR) has been explored as a suitable material for fabricating implants for patients with metal allergy. In this study, we examined the effect of UV treatment on the NANOZR surface. The experimental group was UV-treated NANOZR and the control group was untreated NANOZR. Observation of the surface of the UV-treated materials revealed no mechanical or structural change; however, the carbon content on the material surface was reduced, and the material surface displayed superhydrophilicity. Further, the effects of the UV-induced superhydrophilic properties of NANOZR plates on the adhesion behavior of various cells were investigated. Treatment of the NANOZR surface was found to facilitate protein adsorption onto it. An in vitro evaluation using rat bone marrow cells, human vascular endothelial cells, and rat periodontal ligament cells revealed high levels of adhesion in the experimental group. In addition, it was clarified that the NANOZR surface forms active oxygen and suppresses the generation of oxidative stress. Overall, the study results suggested that UV-treated NANOZR is useful as a new ceramic implant material. Full article
(This article belongs to the Special Issue The Application of Nano-Modified Titanium)
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14 pages, 4057 KiB  
Article
Decontamination of Titanium Surface Using Different Methods: An In Vitro Study
by Sifan Yan, Min Li, Satoshi Komasa, Akinori Agariguchi, Yuanyuan Yang, Yuhao Zeng, Seiji Takao, Honghao Zhang, Yuichiro Tashiro, Tetsuji Kusumoto, Yasuyuki Kobayashi, Liji Chen, Kosuke Kashiwagi, Naoyuki Matsumoto, Joji Okazaki and Takayoshi Kawazoe
Materials 2020, 13(10), 2287; https://doi.org/10.3390/ma13102287 - 15 May 2020
Cited by 6 | Viewed by 2586
Abstract
Contamination of implants is inevitable during different steps of production as well as during the clinical use. We devised a new implant cleaning strategy to restore the bioactivities on dental implant surfaces. We evaluated the efficiency of the Finevo cleaning system, and Ultraviolet [...] Read more.
Contamination of implants is inevitable during different steps of production as well as during the clinical use. We devised a new implant cleaning strategy to restore the bioactivities on dental implant surfaces. We evaluated the efficiency of the Finevo cleaning system, and Ultraviolet and Plasma treatments to decontaminate hydrocarbon-contaminated titanium disks. The surfaces of the contaminated titanium disks cleaned using the Finevo cleaning system were similar to those of the uncontaminated titanium disks in scanning electron microscopy and X-ray photoelectron spectroscopy analysis, but no obvious change in the roughness was observed in the scanning probe microscopy analysis. The rat bone marrow mesenchymal stem cells (rBMMSCs) cultured on the treated titanium disks attached to and covered the surfaces of disks cleaned with the Finevo cleaning system. The alkaline phosphatase activity, calcium deposition, and osteogenesis-related gene expression in rBMMSCs on disks cleaned using the Finevo cleaning system were higher compared to those in the ultraviolet and plasma treatments, displaying better cell functionality. Thus, the Finevo cleaning system can enhance the attachment, differentiation, and mineralization of rBMMSCs on treated titanium disk surfaces. This research provides a new strategy for cleaning the surface of contaminated titanium dental implants and for restoration of their biological functions. Full article
(This article belongs to the Special Issue The Application of Nano-Modified Titanium)
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