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Innovations in Dental Biomaterials: Mechanical Properties and Bonding Challenges

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 20 April 2026 | Viewed by 954

Special Issue Editors


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Guest Editor
Department of Endodontics and Restorative Dentistry, School of Dental Medicine University of Zagreb, 10000 Zagreb, Croatia
Interests: dental materials; restorative dentistry
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Endodontics and Restorative Dentistry, School of Dental Medicine University of Zagreb, 10000 Zagreb, Croatia
Interests: dental materials; dental pulp regeneration; endodontics; restorative dentistry

Special Issue Information

Dear Colleagues,

We are pleased to announce a forthcoming Special Issue dedicated to biointeractive restorative materials, a rapidly evolving field at the intersection of material science, biomedicine, and clinical innovation. We invite submissions exploring novel approaches, materials, and technologies that integrate bioactivity into dental medicine.

As dentistry continues to evolve toward minimally invasive and biologically driven solutions, innovative materials that combine mechanical reliability with superior bonding to tooth structures are critical. Interesting topics include changes in the production and composition of dental materials and new application techniques, but also issues in the field of the impact of environmental factors on the long-term survival of dental fillings in the oral cavity. Additionally, articles may cover composite resins, glass ionomer cements, root canal fillings and dental ceramics.

This Special Issue aims to showcase cutting-edge original articles, alongside clinical studies, communications, and reviews, that redefine how restorative materials interact with biological systems to promote healing, regeneration, and long-term functionality.

Prof. Dr. Ivana Miletić
Guest Editor

Dr. Anja Ivica
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • biointeractive materials
  • bonding agents
  • dental materials
  • dentin adhesion
  • glass ionomer cements
  • minimally invasive dentistry
  • remineralization
  • restorative dentistry
  • smart materials

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Published Papers (1 paper)

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Research

18 pages, 2898 KB  
Article
Exploring the Biological and Chemical Properties of Emerging 3D-Printed Dental Resin Composites Compared to Conventional Light-Cured Materials
by Nikola Živković, Stefan Vulović, Miloš Lazarević, Anja Baraba, Aleksandar Jakovljević, Mina Perić, Jelena Mitrić and Aleksandra Milić Lemić
Materials 2025, 18(22), 5170; https://doi.org/10.3390/ma18225170 - 14 Nov 2025
Viewed by 550
Abstract
Advances in additive manufacturing have accelerated the development of 3D-printed dental resin composites. These materials contain a higher proportion of organic matrix and less filler than light-cured representatives, which may affect their behavior in the oral environment. This study aimed to evaluate the [...] Read more.
Advances in additive manufacturing have accelerated the development of 3D-printed dental resin composites. These materials contain a higher proportion of organic matrix and less filler than light-cured representatives, which may affect their behavior in the oral environment. This study aimed to evaluate the biological and chemical properties of 3D-printed dental resin composites before and after artificial aging, and to compare them with the light-cured representative. Specimens from a light-cured composite (Omnichroma—OMCR) and two 3D-printed composites (GT Temp PRINT—GTPR; SprintRay CROWN—SPRY) were subjected to aging treatments: unaged (T0) or thermocycled for 5000 (T1) and 10,000 cycles (T2). Biological evaluation was performed using MTT assay and Live/Dead cell fluorescence microscopy using human gingival fibroblasts, whereas Raman spectroscopy analysed materials’ structural changes. Materials exhibited good biocompatibility (>70% cell viability), with OMCR displaying greater variability. OMCR was more susceptible to chemical degradation under thermal stresses than both 3D-printed materials. Tested 3D-printed composites can provide comparable or even superior biological and chemical properties compared to light-cured representative, likely due to optimized resin formulations and post-curing protocols that improve polymer network organization and reduce residual monomer release. These findings support the potential of tested 3D-printed composites for manufacturing dental restorations. Full article
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