Exploring Hydrogen-Bonded Organic Framework Materials in Biomedical Applications
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: 10 September 2026
Special Issue Editor
Special Issue Information
Dear Colleagues,
The rapid advancement of nanomedical technology has established porous materials as a critical platform in novel nanomedicine. Further expanding the application scope and research depth of nanoporous materials in biomedicine, hydrogen-bonded organic frameworks (HOFs) are emerging as a new generation of nanoporous materials, distinguished by their excellent biocompatibility, structural tunability, and functional diversity. This Special Issue aims to systematically promote the exploration of HOFs in biomedical applications, with a focus on key scientific challenges such as the regulation of bioactivity, structural stability, in vivo safety, and the construction of intelligent functionalities. We seek to provide novel research perspectives and stimulate further development in this evolving field.
A central challenge lies in effectively balancing the stability and biodegradability of HOFs under physiological conditions, while simultaneously improving their biosafety, enhancing biocatalytic activity, and elevating therapeutic efficacy. Topics of interest for this issue include, but are not limited to, the design of novel HOF structures, nanozyme development, bioorthogonal catalytic systems, intelligent drug release platforms, and in vivo metabolic pathway investigations. We cordially invite original contributions that present innovative ideas and methodologies, as well as high-quality review articles and case studies, to collectively advance the scientific understanding and practical translation of HOFs in biomedicine.
Dr. Dongqin Yu
Guest Editor
Manuscript Submission Information
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Keywords
- hydrogen-bonded organic frameworks
- biomedical applications
- crystalline structure
- biocatalysts
- drug delivery
- nanozymes
- stability
- biosecurity
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