Special Issue "Structure–Activity Relationship of Marine Bioactive Compounds"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: 20 December 2020.
Interests: marine natural products; isolation and structural elucidation; organic synthesis; biological activity; medicinal chemistry; bacterial iron uptake; siderophores
Special Issues and Collections in MDPI journals
Marine organisms constitute a rich source of biologically active and chemically diverse natural products and serve as an invaluable resource in the ongoing search for novel bioactive compounds. A rational study provides information on the design of compounds or the understanding of the mechanism, or clarifies the discovery, design or optimization of new potent compounds as biological agents. The relationship between chemical structure and biological activity is related to the specific action of a bioactive marine natural product. For that reason, the determination of structure–activity relationships of these bioactive molecules is a crucial step in their development as a new drug, agrochemical, cosmetic or other application based on their activity. Studies on the influence on the bioactivity of the size, shape, and degree of ionization of bioactive Marine Natural Products is a topic of growing interest nowadays due to its potential applications with increased potency, greater selectivity, higher stability, and lower toxicity. Current research also focuses on the molecular modifications of reported series that lead to a significantly improved understanding of their structure–activity relationships. As Guest Editor of this Special Issue of Marine Drugs, I invite you to provide recent advances in all the aspects dealing with the structure–activity relationship of marine bioactive compounds.
Prof. Dr. Carlos Jimenez
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Marine natural products
- Biological activity
- Drug discovery
- Structure–activity relationships
- Synthetic and natural analogs
- Elucidation of pharmacophore
- Biological action mechanism
- Target protein on the bioactive substances
- Quantitative structure–activity relationships (QSAR)
- ADMET studies
- Molecular modeling
- Combinatorial chemistry