New Development and Application of Next Generation Sequencing
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".
Deadline for manuscript submissions: closed (21 July 2023) | Viewed by 3501
Special Issue Editors
Interests: next generation sequencing; sequencing; NGS data analysis; transcriptomics; genomics; bioinformatics and computational biology
Interests: bioinformatics; next generation sequencing; genomics; bioinformatics and computational biology
2. European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, UK
Interests: bioinformatics; next generation sequencing; single-cell biology
Special Issue Information
Dear Colleagues,
In the past 10-15 years, the next-generation sequencing (NGS) technologies have revolutionized many fields in biology and medicine. In human genomics, the $1000 genome goal has been achieved and now technology industries are aiming to get a human WGS under $100. This further drastically reduced sequencing cost together with international projects such as 1+Million Genomes Initiative have demanded new experimental and computational methods and FAIR data infrastructure in order to tackle this next wave of data tsunami. Besides the population scale expansion, we are also deepening our understanding at the individual level thanks to the fast adoption of single cell sequencing technology. Projects like Human Cell Atlas are linking researchers around the world to share and integrate tissue and organ profiles at single cell level to answer crucial fundamental questions in cancer genetics, neurology, stem cell based treatment, etc. Furthermore, in the areas of plant, animal and microbiome, new long read sequencing technologies and gene editing toolings are being applied routinely to provide unprecedented insight to move the science forward.
In this special issue, we encourage researchers to submit unpublished research work addressing new development and application of NGS including the following but not limited to:
- NGS based disease prediction
- Personalized cancer treatment
- Single cell transcriptomic and spatial transcriptomics
- Virus detection and classification
- Gene modification using CRISPR/Cas9
- Plant genomics
- Metagenomics
Dr. Hailiang Mei
Dr. Andrew P. Stubbs
Dr. Wendi Bacon
Guest Editors
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Keywords
- NGS based disease prediction
- personalized cancer treatment
- single cell transcriptomic and spatial
- virus detection and classification
- gene modification using CRISPR/Cas9
- plant genomics
- metagenomics
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