The Microbiome in Liver Disease: Current Issues and Future Perspectives
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (26 August 2022) | Viewed by 2537
Special Issue Editor
2. 1st Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany
Interests: chronic liver diseases; alcohol liver disease; autoimmune liver disease; gut–liver axis; microbiome; gut microbiota; nonalcoholic fatty liver disease; immune system; metabolites
Special Issue Information
Dear Colleagues,
The human commensal microbiome is a complex and dynamic consortium of microorganisms intricately connected to human physiology in health and disease. The liver is a critical immune organ hosting a wealth of immune cells and processing microbial signals originating from the intestine at the crossroads of the portal and systemic circulations. Understanding the interplay between hepatic immunology and the microbiome has shed new light on the pathophysiology of liver diseases with significant epidemiological relevance. There is a wealth of clinical microbiome studies associating liver diseases with commensal microbial alterations. Of immense importance is the step from high-throughput sequencing establishing correlation to mechanistic studies proving causality and paving the way for therapeutic intervention.
The present collection aims to identify recent advances in the understanding of microbiome-liver interactions in health and disease and its impact on the diagnosis and treatment of liver diseases, providing an up-to-date perspective.
Dr. Timur Liwinski
Guest Editor
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Keywords
- chronic liver diseases
- alcohol liver disease
- autoimmune liver disease
- gut–liver axis; microbiome
- gut microbiota
- nonalcoholic fatty liver disease
- immune system
- metabolites
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