Chronic Pain: From Molecular Mechanisms to Targeted Interventions

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 165

Special Issue Editors


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Guest Editor
Graduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 404328, Taiwan
Interests: chronic pain; depression; TRPV1; signaling pathway; neuroscience; brain sciences
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Acupuncture and Meridian Science Research Center, Kyung Hee University, Seoul 02453, Republic of Korea
Interests: brain cognitive engineering; acupuncture; neuroimaging; neuromodulation; pain
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite you to contribute to this Special Issue of Life, entitled ‘Chronic Pain: From Molecular Mechanisms to Targeted Interventions’.

Chronic pain, which defined as pain signals lasting more than three months in clinical observation, differs from acute pain, which serves as a warning sign. Due to its complex mechanisms and difficulty in treatment, it has become a major global health challenge. Currently, approximately one to two billion people worldwide suffer from it, resulting in a heavy socioeconomic burden and high healthcare costs. The National Institutes of Health (NIH) emphasizes that, given the difficulties in clinically treating chronic pain, developing new interventions to improve patients' physical and mental health and quality of life is an urgent priority.

Currently, there is still a lack of effective treatments for chronic pain. Methods for pain management include analgesics, antiepileptic drugs, neurostimulation, traditional medicine, physical therapy, artificial intelligence, neuroimaging, and placebos. This Special Issue invites submissions from researchers and physicians in any field, including original research/review articles, on various treatment methods such as medication, neurostimulation, neuroimaging, neurobiology, clinical trials, or artificial intelligence. This Special Issue aims to promote the discovery of the mechanisms, diagnosis, treatment, and management of chronic pain.

Prof. Dr. Yiwen Lin
Prof. Dr. Younbyoung Chae
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chronic pain
  • analgesics
  • neurostimulation
  • traditional medicine
  • physical therapy
  • neuroimaging

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