Neurodegenerative Diseases: From Risk Factors to Treatments
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (28 April 2026) | Viewed by 1122
Special Issue Editor
Interests: dementia; neuropsychiatric symptoms; neuropsychology; psychobiology; natural compounds; information and communication technology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases share some fundamental characteristics, including the gradual progression of symptoms and the significant impact on the autonomy and quality of patients’ lives. Despite the different causes and manifestations, the common denominator is the deterioration of neural capacities, which leads to motor difficulties, memory problems, mood changes, and other complications.
The exact causes of neurodegenerative diseases are not always clear, but numerous studies suggest an interaction between genetic, environmental, and lifestyle factors.
The central focus of this Special Issue will be to advance novel therapeutic models that have shown exceptional promise in clinical models of NDs. The aim will be to individualize genetic and clinic mechanisms of NDs considering age-related and multidimensional approaches for the purpose of appropriate and personalized treatment, along with the use of information and communication technology (ICT) tools, which can decrease hospitalization and increase permanence at home.
Pharmacologic treatment delivers limited symptomatic benefits, so the provision of non-pharmacological treatments in addition to standard outpatient care is an asset of good clinical practice.
Therefore, prognostic evaluation of patients with NDs plays a key role in the decision analyses of care processes including the organization of the social health care system, the support to families, caregivers, and patients, as well as the choice of appropriate treatment.
Dr. Grazia D’Onofrio
Guest Editor
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Keywords
- immune regulation (e.g., chronic inflammation) of NDs
- cardiocerebral vascular disease and NDs
- the effects of emotional and affective dimensions on cognitive reserve decline
- the multidimensional screening of NDs
- the interventions of NDs
- gene polymorphism on the efficacy of pharmacological treatments in NDs
- cognitive and functional rehabilitation for patients with NDs
- technology innovation in the integrated approach to the patients with NDs
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