Advances in Dialysis Pathology: Insights into Peritoneal and Hemodialysis Complications

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 December 2025 | Viewed by 612

Special Issue Editor


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Guest Editor
Division of Pediatric Immunology and Nephrology, Department of Pediatrics, Taipei Veterans General Hospital, Taipei 11221, Taiwan
Interests: acute and chronic kidney disease; early prediction; molecular diagnosis; precision therapy
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Special Issue Information

Dear Colleagues,

This Special Issue focuses on the pathological features and complications arising in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD). It aims to provide a comprehensive understanding of the structural and functional changes associated with long-term dialysis, with particular attention on cardiovascular complications, vascular pathology including arteriovenous fistula (AVF) alterations, and morphological changes in the peritoneal membrane in chronic PD patients.

We welcome contributions that explore the mechanisms and histopathological findings of dialysis-associated infections, dialysis-related organ damage, and the role of tissue pathology in informing clinical decision-making. By highlighting the intersection between clinical nephrology and pathology, this issue seeks to deliver practical insights for researchers and clinicians involved in the management of dialysis-related complications.

Dr. Chien-Hung Lin
Guest Editor

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Keywords

  • peritoneal dialysis
  • hemodialysis
  • acute kidney injury (AKI)
  • chronic kidney disease
  • pathology
  • complication

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Published Papers (1 paper)

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Research

10 pages, 419 KB  
Article
Association of Phase Angle with Body Composition in Hemodialysis Patients: A Case–Control Study
by Selma Cvijetić Avdagić, Petra Kovačević Totić, Karla Kovačević Čorak, Antonija Sulimanec and Karmela Altabas
Life 2025, 15(11), 1666; https://doi.org/10.3390/life15111666 - 25 Oct 2025
Viewed by 431
Abstract
Patients on hemodialysis (HD) often experience changes in body composition due to metabolic disorders. Phase angle (PhA) is a marker of tissue integrity and may reflect overall functional condition. This study evaluated body composition and its relationship with PhA in 53 HD patients [...] Read more.
Patients on hemodialysis (HD) often experience changes in body composition due to metabolic disorders. Phase angle (PhA) is a marker of tissue integrity and may reflect overall functional condition. This study evaluated body composition and its relationship with PhA in 53 HD patients (27 women, 26 men) over 40 years old, compared with 106 age- and sex-matched healthy controls. Body composition was assessed using bioelectrical impedance analysis (BIA), measuring skeletal muscle mass (SMM), fat tissue, total bone mass (BM), and PhA. HD patients had significantly lower fat mass and PhA than controls (p < 0.001). The prevalence of low SMM and BM was higher in patients, though not statistically significant. Sex differences were generally not significant, except for a higher prevalence of low BM in female controls (p < 0.001). After adjusting for age and sex, PhA was positively associated with SMM% (p = 0.021) and BM (p = 0.035) in HD patients only. These results indicate that PhA–body composition relationships differ between HD patients and healthy individuals, highlighting PhA as a potential marker of body composition disturbances in HD. Full article
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