Impact of Circulating Ketones on Physiology

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 October 2024 | Viewed by 115

Special Issue Editor

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Guest Editor
Department of Kinesiology, Augusta University, Augusta, GA, USA
Interests: ketone supplementation; stress; nutrition; tactical athletes; sleep health; cardiovascular health; body composition; physical performance

Special Issue Information

Dear Colleagues,

A Special Issue has been set up to incorporate papers that illustrate the consequences of elevating ketone levels on physiological changes in animal or human models. This Special Issue, edited by Dr. Maleah Winkler, will focus on the physiological effects that occur due to dietary alterations (i.e., ketogenic diet, prolonged fasting) or ketone supplementation. Beta-hydroxybutyrate, a ketone molecule that is measured in the blood to determine ketone status as well as commonly found in supplements, has been shown to act as both a signaling molecule and fuel source for extra-hepatic tissues. As a signaling molecule, beta-hydroxybutyrate has been shown to possibly reduce inflammation and sympathetic activation, while as a fuel source, it has been shown to improve tissue health, and cognitive and exercise performance. More studies revolving around these concepts would allow more depth and understanding to this popular topic. This issue seeks to exhibit related physiological commonalities as well as controversies that experts are finding after increasing circulating ketone levels

Dr. Maleah Winkler
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • ketones
  • ketone supplementation
  • beta-hydroxybutyrate
  • ketogenic diet
  • fasting

Published Papers

This special issue is now open for submission.
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