Metabolic Adaptations to Environmental Pressure
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (23 October 2020) | Viewed by 3854
Special Issue Editor
Special Issue Information
Dear colleagues,
Energy and nutrient fluctuations require finely regulated metabolic systems. Much of the development and evolution of these systems has taken place in the absence of pressures that we now experience as modern humans, including nutrient overload, lack of physical activity, and exposure to thermoneutral conditions and radiations. Overall, these environmental inputs ignite adaptive responses, which persist dramatically due to both increase in life expectancy and chronic lifetime exposure to stress signals. A metabolic pressure is then generated that, if continuous, may lead to metabolic and immunological failure, thus causing reduced tolerance to glucose and infections. In fact, biological responses are unable to cope with these challenges, and homeostatic systems gradually deteriorate.
For this Life Special Issue, submissions are encouraged to discuss how metabolic workload can modulate stress tolerance and to identify the molecular checkpoints governing the adaptive responses. Novel strategies aimed at restoring metabolic homeostasis under conditions of metabolic pressure are also welcome.
Dr. Daniele Lettieri-Barbato
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- nutrient partitioning
- metabolism
- adaptive stress responses
- mitochondrial bioenergetics
- metabolic flexibility/inflexibility
- adaptations to nutrient overload/restrictions
- adaptations to redox pressure
- adaptations to cool temperature
- adipose tissues
- adipocytes
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
