Innovations in Tissue Reconstruction and Wound Repair
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 28 August 2026 | Viewed by 170
Special Issue Editor
Interests: tissue reconstruction; microsurgery; wound healing; biomaterials; regenerative medicine; AI in surgery; translational innovation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Advances in tissue reconstruction and wound repair are increasingly arising from a deeper understanding of the biological, mechanistic, and translational processes that govern tissue injury, repair, and regeneration. Beyond surgical technique alone, contemporary progress is driven by insights into inflammation, fibroproliferative signalling, angiogenesis, extracellular matrix remodelling, immune modulation, and mechanobiology, with a special emphasis on the application of biomaterials and stem cells. This progress is coupled with diagnostic and biomarker-guided strategies that enable personalised intervention.
This Special Issue, titled “Innovations in Tissue Reconstruction and Wound Repair”, aims to highlight high-quality basic, translational, and clinically integrated research that bridges bench-to-bedside innovation, with a key focus on biomaterials and stem cell-based regenerative approaches. We particularly welcome studies that elucidate wound-healing mechanisms, identify diagnostic or prognostic biomarkers, develop and characterise novel biomaterials (e.g., smart hydrogels, 3D-printed scaffolds), explore stem cell biology, delivery, and efficacy, and translate these biological and material discoveries into improved reconstructive outcomes. Topics of interest include, but are not limited to, fibroproliferative and inflammatory wound disorders; tissue perfusion and microvascular biology; stem cell- and scaffold-based therapies; AI-enabled diagnostics and surgical planning; infection and scar modulation; and the integration of biomaterials with cellular therapies for enhanced regeneration. Clinical studies are encouraged when embedded within mechanistic, diagnostic, or translational frameworks.
By integrating biological insight and advances in biomaterial/stem cell science with reconstructive innovation, this Special Issue seeks to advance the science underpinning tissue repair and guide the next generation of therapeutic strategies in reconstructive surgery and wound healing.
Dr. Ishith Seth
Guest Editor
Manuscript Submission Information
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Keywords
- stem cell therapy
- tissue engineering
- tissue reconstruction
- microsurgery
- wound healing
- regenerative medicine
- biomaterials
- perforator flaps
- supermicrosurgery
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