Non-coding RNAs: Genomics, Biogenesis, Mechanisms, and Functions

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 325

Special Issue Editor

Guest Editor
1. Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan
2. Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei 114, Taiwan
Interests: non-coding RNA; melatonin signaling; cancer biology; molecular mechanism; membranous nephropathy

Special Issue Information

Dear Colleagues,

Non-coding RNAs (ncRNAs) represent a diverse group of transcripts that do not encode proteins but play pivotal roles as regulators across various biological functions and species. This category encompasses both housekeeping ncRNAs (e.g., rRNA, snoRNA, pseudogenes, and TERC) and regulatory ncRNAs (such as siRNA, miRNA, eRNA, lncRNA, and circRNA), each holding significant importance. Understanding the regulation of ncRNA levels is crucial for uncovering their biological significance. Quality-control mechanisms govern ncRNA abundance through biogenesis, processing, and degradation pathways. However, there's still a knowledge gap regarding the mechanisms and biological importance of these quality-control systems that manage ncRNA functions.

This Special Issue aims to showcase recent advances in comprehending the molecular mechanisms underlying ncRNA abundance. It predominantly focuses on fundamental research providing novel insights into controlling ncRNA levels, as well as exploring clinical, diagnostic, and therapeutic perspectives of ncRNA-mediated physiological conditions. We welcome the submission of research and review articles exploring these themes.

Dr. Yen-Sung Huang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • ncRNA-interacting proteins
  • ncRNA modification
  • ncRNA biogenesis
  • ncRNA degradation
  • ncRNA decay
  • function
  • disease
  • therapeutic targets

Published Papers

This special issue is now open for submission.
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