Pain Management and Related Complications in the Orthopedics and Neurology

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 3123

Special Issue Editors


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Guest Editor
1. Physical Therapy and Rehabilitation Unit, Policlinico di Modena, 41125 Modena, Italy
2. Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41121 Modena, Italy
Interests: orthopedic rehabilitation; hand and wrist rehabilitation; shoulder; ultrasound; infiltrative treatment
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Guest Editor
IRCCS Rizzoli Orthopaedic Institute, Bologna, Italy
Interests: bone; anterior cruciate ligament; articular cartilage; knee surgery; cartilage; arthroplasty; hip and knee arthroplasty; hip; hip arthroplasty

Special Issue Information

Dear Colleagues,

The management of pain and related complications is one of the main problems in the musculoskeletal field. This special issue aims to investigate therapies and innovations in the field of pain management and possible complications such as infections, tendon, nerve and bone injuries. In the orthopedic and neurological fields there are various pathologies related to pain management for which targeted treatments are also needed to prevent any complications. This special issue of Life aims to provide an expansive platform for the latest research and developments in pain management, rehabilitation, encompassing a wide range of areas including musculoskeletal, orthopedic, neurological, and more. We invite papers that present innovative solutions and approaches, including but not limited to:

  • Pain management of the upper and lower limb
  • Pain management of the spine
  • Orthopaedic rehabilitation
  • Prevention of fall risks Prevention and management infections
  • Muscle, tendon, and joint diseases
  • Neurological impacts on musculoskeletal health

Dr. Danilo Donati
Dr. Francesco Castagnini
Guest Editors

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Keywords

  • pain management of the upper and lower limb
  • pain management of the spine
  • orthopaedic rehabilitation
  • prevention of fall risks prevention and management infections
  • muscle, tendon, and joint diseases
  • neurological impacts on musculoskeletal health

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Published Papers (1 paper)

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15 pages, 1402 KiB  
Systematic Review
Manual Therapy vs. Surgery: Which Is Best for Carpal Tunnel Syndrome Relief?
by Danilo Donati, Paolo Boccolari and Roberto Tedeschi
Life 2024, 14(10), 1286; https://doi.org/10.3390/life14101286 - 11 Oct 2024
Cited by 1 | Viewed by 2848
Abstract
Background: Carpal Tunnel Syndrome (CTS) is a common condition characterized by compression of the median nerve, leading to pain, numbness, and hand dysfunction. Both manual therapy and surgical decompression are widely used interventions, but their comparative effectiveness remains uncertain. Methods: A systematic review [...] Read more.
Background: Carpal Tunnel Syndrome (CTS) is a common condition characterized by compression of the median nerve, leading to pain, numbness, and hand dysfunction. Both manual therapy and surgical decompression are widely used interventions, but their comparative effectiveness remains uncertain. Methods: A systematic review and a meta-analysis were conducted to compare the short- and long-term efficacy of manual therapy versus surgery for CTS. Studies were selected based on randomized controlled trials (RCTs) that met the inclusion criteria, focusing on outcomes such as pain intensity, hand function, symptom severity, and quality of life. Data were extracted and analyzed by using standardized tools to assess treatment effects. Results: Five RCTs with a total of 533 participants were included. Manual therapy was more effective for short-term pain relief, with significant improvements at 1 and 3 months compared with surgery. However, at 6 to 12 months, surgical intervention provided greater improvements in hand function and symptom severity. Quality-of-life improvements were similar in both groups. Risk of bias was moderate to low across the studies, with limitations in blinding due to the nature of the interventions. Conclusions: Manual therapy offers effective short-term relief for CTS, making it a viable option for patients with mild to moderate symptoms. Surgery provides more durable, long-term outcomes, particularly for severe cases. The choice of treatment should be individualized, considering patient preferences and symptom severity. Full article
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