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Life
Special Issues
Pain Management and Related Complications in the Orthopedics and Neurology
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Pain Management and Related Complications in the Orthopedics and Neurology

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 May 2025 | Viewed by 3455

Special Issue Editors

Dr. Danilo Donati

E-Mail Website
Guest Editor
1. Physical Therapy and Rehabilitation Unit, Policlinico di Modena, 41125 Modena, Italy
2. Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, 41121 Modena, Italy
Interests: orthopedic rehabilitation; hand and wrist rehabilitation; shoulder; ultrasound; infiltrative treatment
Special Issues, Collections and Topics in MDPI journals
Dr. Francesco Castagnini

E-Mail Website
Guest Editor
IRCCS Rizzoli Orthopaedic Institute, Bologna, Italy
Interests: bone; anterior cruciate ligament; articular cartilage; knee surgery; cartilage; arthroplasty; hip and knee arthroplasty; hip; hip arthroplasty

Special Issue Information

Dear Colleagues,

The management of pain and related complications is one of the main problems in the musculoskeletal field. This special issue aims to investigate therapies and innovations in the field of pain management and possible complications such as infections, tendon, nerve and bone injuries. In the orthopedic and neurological fields there are various pathologies related to pain management for which targeted treatments are also needed to prevent any complications. This special issue of Life aims to provide an expansive platform for the latest research and developments in pain management, rehabilitation, encompassing a wide range of areas including musculoskeletal, orthopedic, neurological, and more. We invite papers that present innovative solutions and approaches, including but not limited to:

  • Pain management of the upper and lower limb
  • Pain management of the spine
  • Orthopaedic rehabilitation
  • Prevention of fall risks Prevention and management infections
  • Muscle, tendon, and joint diseases
  • Neurological impacts on musculoskeletal health

Dr. Danilo Donati
Dr. Francesco Castagnini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pain management of the upper and lower limb
  • pain management of the spine
  • orthopaedic rehabilitation
  • prevention of fall risks prevention and management infections
  • muscle, tendon, and joint diseases
  • neurological impacts on musculoskeletal health

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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15 pages, 1402 KiB  
Systematic Review
Manual Therapy vs. Surgery: Which Is Best for Carpal Tunnel Syndrome Relief?
by Danilo Donati, Paolo Boccolari and Roberto Tedeschi
Life 2024, 14(10), 1286; https://doi.org/10.3390/life14101286 - 11 Oct 2024
Cited by 3 | Viewed by 3167
Abstract
Background: Carpal Tunnel Syndrome (CTS) is a common condition characterized by compression of the median nerve, leading to pain, numbness, and hand dysfunction. Both manual therapy and surgical decompression are widely used interventions, but their comparative effectiveness remains uncertain. Methods: A systematic review [...] Read more.
Background: Carpal Tunnel Syndrome (CTS) is a common condition characterized by compression of the median nerve, leading to pain, numbness, and hand dysfunction. Both manual therapy and surgical decompression are widely used interventions, but their comparative effectiveness remains uncertain. Methods: A systematic review and a meta-analysis were conducted to compare the short- and long-term efficacy of manual therapy versus surgery for CTS. Studies were selected based on randomized controlled trials (RCTs) that met the inclusion criteria, focusing on outcomes such as pain intensity, hand function, symptom severity, and quality of life. Data were extracted and analyzed by using standardized tools to assess treatment effects. Results: Five RCTs with a total of 533 participants were included. Manual therapy was more effective for short-term pain relief, with significant improvements at 1 and 3 months compared with surgery. However, at 6 to 12 months, surgical intervention provided greater improvements in hand function and symptom severity. Quality-of-life improvements were similar in both groups. Risk of bias was moderate to low across the studies, with limitations in blinding due to the nature of the interventions. Conclusions: Manual therapy offers effective short-term relief for CTS, making it a viable option for patients with mild to moderate symptoms. Surgery provides more durable, long-term outcomes, particularly for severe cases. The choice of treatment should be individualized, considering patient preferences and symptom severity. Full article
(This article belongs to the Special Issue Pain Management and Related Complications in the Orthopedics and Neurology)
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