Pleural and Pulmonary Fibrosis: Pathogenesis and Possible Treatment Strategies
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 62
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue aims to explore the complex mechanisms underlying the development of pleural and pulmonary fibrosis, especially the cellular and molecular processes involved. Pulmonary fibrosis is characterized by excessive scarring and thickening of lung tissue, leading to impaired gas exchange and progressive respiratory failure. This Special Issue aims to delve into the role of inflammatory responses, epithelial cell dysfunction, and fibroblast activation in fibrosis progression, as well as other disease contributors including (but not limited to) genetic factors, environmental exposure, and aberrant immune system activation.
This Special Issue will further review various potential therapeutic approaches, from anti-inflammatory and antifibrotic agents to novel molecular-targeted therapies. It will highlight promising drugs in clinical trials aimed at modulating fibrosis pathways, thereby improving lung function and slowing disease progression. Strategies such as gene therapy, stem cell-based treatments, and precision medicine are also welcome for discussion as future directions in managing fibrotic lung diseases. This Special Issue will emphasize the need for early detection, better diagnostic tools, and a multidisciplinary approach to optimize treatment outcomes for patients with pleural and pulmonary fibrosis, providing a comprehensive overview of current understanding and therapeutic advancements in the field.
Dr. Oluwaseun Adeyanju
Guest Editor
Manuscript Submission Information
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Keywords
- pulmonary fibrosis
- pleural fibrosis
- pathogenesis
- therapeutic strategies
- inflammation
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