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15 December 2023
Life | Hot Papers on Liquid Biopsy

Liquid biopsy provides the opportunity of detecting, analyzing, and monitoring cancer in various body effluents such as blood or urine instead of a fragment of cancer tissue. Liquid biopsies can detect changes in tumor burden months or years before conventional imaging tests can, making them suitable for early tumor detection, monitoring, and detection of resistance mutations. Much of the early research on liquid biopsies has been in lung, breast, and prostate cancers, but this technology is expected to have an impact on all types of cancer.

1. “Liquid Biopsy, ctDNA Diagnosis through NGS”

by Chen Lin, Xuzhu Liu, Bingyi Zheng, Rongqin Ke and Chi-Meng Tzeng

Life 2021, 11(9), 890; https://doi.org/10.3390/life11090890

Available online: https://www.mdpi.com/2075-1729/11/9/890

2. “Machine Learning Protocols in Early Cancer Detection Based on Liquid Biopsy: A Survey”

by Linjing Liu, Xingjian Chen, Olutomilayo Olayemi Petinrin, Weitong Zhang, Saifur Rahaman, Zhi-Ri Tang and Ka-Chun Wong

Life 2021, 11(7), 638; https://doi.org/10.3390/life11070638

Available online: https://www.mdpi.com/2075-1729/11/7/638

3. “Liquid Biopsy and Potential Liquid Biopsy-Based Biomarkers in Philadelphia-Negative Classical Myeloproliferative Neoplasms: A Systematic Review”

by Mihnea-Alexandru Găman, Matei-Alexandru Cozma, Elena-Codruța Dobrică, Sanda Maria Crețoiu, Amelia Maria Găman and Camelia Cristina Diaconu

Life 2021, 11(7), 677; https://doi.org/10.3390/life11070677

Available online: https://www.mdpi.com/2075-1729/11/7/677

4. “The World of Pseudogenes: New Diagnostic and Therapeutic Targets in Cancers or Still Mystery Molecules?”

by Maciej Stasiak, Tomasz Kolenda, Joanna Kozłowska-Masłoń, Joanna Sobocińska, Paulina Poter, Kacper Guglas, Anna Paszkowska, Renata Bliźniak, Anna Teresiak, Urszula Kazimierczak at el.

Life 2021, 11(1), 69; https://doi.org/10.3390/life11010069

Available online: https://www.mdpi.com/2075-1729/11/1/69

5. “Liquid Biopsy in Diagnosis and Prognosis of High-Grade Gliomas; State-of-the-Art and Literature Review”

by Lapo Bonosi, Gianluca Ferini, Giuseppe Roberto Giammalva, Umberto Emanuele Benigno, Massimiliano Porzio, Evier Andrea Giovannini, Sofia Musso, Rosa Maria Gerardi, Lara Brunasso, Roberta Costanzo at el.

Life 2022, 12(3), 407; https://doi.org/10.3390/life12030407

Available online: https://www.mdpi.com/2075-1729/12/3/407

6. “Cancer Type Classification in Liquid Biopsies Based on Sparse Mutational Profiles Enabled through Data Augmentation and Integration”

by Alexandra Danyi, Myrthe Jager and Jeroen de Ridder

Life 2022, 12(1), 1; https://doi.org/10.3390/life12010001

Available online: https://www.mdpi.com/2075-1729/12/1/1

7. “The Overview of Perspectives of Clinical Application of Liquid Biopsy in Non-Small-Cell Lung Cancer”

by Aleksandra Bożyk and Marcin Nicoś

Life 2022, 12(10), 1640; https://doi.org/10.3390/life12101640

Available online: https://www.mdpi.com/2075-1729/12/10/1640

8. “Potential Role of Tumor-Derived Exosomes in Non-Small-Cell Lung Cancer in the Era of Immunotherapy”

by Alfredo Tartarone, Rosa Lerose, Marina Tartarone and Michele Aieta

Life 2022, 12(12), 2104; https://doi.org/10.3390/life12122104

Available online: https://www.mdpi.com/2075-1729/12/12/2104

9. “Association of Circulating Tumor Cells with Inflammatory and Biomarkers in the Blood of Patients with Metastatic Castration-Resistant Prostate Cancer”

by Gerit Theil, Carlotta Lindner, Joanna Bialek and Paolo Fornara

Life 2021, 11(7), 664; https://doi.org/10.3390/life11070664

Available online: https://www.mdpi.com/2075-1729/11/7/664

10. “Current Status of Next-Generation Sequencing-Based Cancer Genome Profiling Tests in Japan and Prospects for Liquid Biopsy”

by Yumi Yoshii, Shunsuke Okazaki and Masayuki Takeda

Life 2021, 11(8), 796; https://doi.org/10.3390/life11080796

Available online: https://www.mdpi.com/2075-1729/11/8/796

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