Hepato-Pancreatic-Biliary Surgery: New Perspectives in Precision Medicine Era

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 1222

Special Issue Editor


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Guest Editor
1. Department of Life Science, Health, and Health Professions, Link Campus University School of Medicine, Via del Casale di San Pio V 44, 00165 Rome, Italy
2. Surgery Center, Colorectal Surgery Research Unit, Fondazione Policlinico Universitario Campus Bio-Medico, University Campus Bio-Medico of Rome, Via Alvaro del Portillo 200, 00128 Rome, Italy
Interests: minimally invasive surgery; acute care surgery; surgical education; GI and colorectal surgery; HPB surgery; personalized medicine; treatment of surgical diseases
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Special Issue Information

Dear Colleagues,

In the realm of hepato-pancreatic–biliary surgery, the precision medicine era brings about profound advancements. Integrating genomics and proteomics with surgical practices revolutionizes our understanding of disorders, empowering tailored interventions for optimal outcomes. This Special Issue highlights research elucidating genetic predispositions, molecular pathways, and personalized treatments through basic science, clinical trials, and population studies. From identifying genetic markers for hepatobiliary malignancies to understanding gut microbiota's role in pancreatic diseases, the research breadth is vast. Additionally, artificial intelligence aids in predictive modeling for treatment responses. Collaboration among clinicians, researchers, and technologists is crucial to navigate this transformative era, fostering precision, efficacy, and improved patient outcomes.

For these reasons, we invite you to contribute to this Special Issue, entitled "Hepato-Pancreatic–Biliary Surgery: New Perspectives in Precision Medicine Era", to report on the techniques, current treatments, and ongoing research, along with the short- and long-term outcomes of HPB surgery related to precision medicine and tailored approaches.

Dr. Gianluca Costa
Guest Editor

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Keywords

  • hepato-pancreatic–biliary surgery
  • precision medicine
  • genomics
  • proteomics
  • nanotechnologies
  • molecular pathways
  • artificial intelligence
  • predictive modeling

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Published Papers (1 paper)

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Review

25 pages, 7126 KiB  
Review
Radiological Assessment After Pancreaticoduodenectomy for a Precision Approach to Managing Complications: A Narrative Review
by Fabrizio Urraro, Vittorio Patanè, Alfredo Clemente, Nicoletta Giordano, Damiano Caputo, Roberto Cammarata, Gianluca Costa and Alfonso Reginelli
J. Pers. Med. 2025, 15(6), 220; https://doi.org/10.3390/jpm15060220 - 28 May 2025
Viewed by 873
Abstract
Radiological assessment following pancreaticoduodenectomy is critical for the prompt diagnosis and management of postoperative complications, significantly influencing patient outcomes. Pancreaticoduodenectomy, or the Whipple procedure, is the standard surgical intervention for pancreatic and periampullary malignancies, but it involves notable risks, especially from complications like [...] Read more.
Radiological assessment following pancreaticoduodenectomy is critical for the prompt diagnosis and management of postoperative complications, significantly influencing patient outcomes. Pancreaticoduodenectomy, or the Whipple procedure, is the standard surgical intervention for pancreatic and periampullary malignancies, but it involves notable risks, especially from complications like fistulas, bleeding, or leakage. Cross-sectional imaging, particularly contrast-enhanced computed tomography, serves as the primary diagnostic tool due to its rapid acquisition, high resolution, and effective delineation of postoperative anatomy and complications. Magnetic resonance imaging (with cholangiopancreatography and hepatobiliary contrast agents) complements CT by providing superior contrast resolution for specific complications, notably in the biliary system and pancreatic duct. This narrative review discusses various imaging techniques and their applications, highlighting characteristic radiological features of common postoperative complications. It underscores the importance of a multidisciplinary approach, emphasizing close collaboration between radiologists and surgeons to optimize surgical decision-making and improve patient management post-pancreatic surgery. Full article
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