Personalized Therapy and Clinical Outcomes for Heart Failure

Dear Colleagues,

Heart failure remains one of the leading causes of morbidity and mortality worldwide, despite major advances in pharmacological and device-based therapies. Its clinical presentation, trajectory, and therapeutic response are highly heterogeneous, reflecting complex interactions between molecular pathways, comorbidities, hemodynamics, and genetic determinants. Over the last decade, the field has shifted toward precision strategies aimed at tailoring interventions to individual patient profiles.

This Special Issue focuses on the integration of personalized approaches into the management of both acute and chronic heart failure. We aim to showcase research that advances phenotyping, risk stratification, biomarkers, imaging, genetics, and treatment optimization. Cutting-edge contributions on novel therapeutic targets, digital health tools, and real-world clinical outcomes are particularly encouraged.

We welcome original research articles, reviews, and clinical studies that help refine our understanding of how individualized strategies can improve prognosis and optimize patient care across the heart failure spectrum.

Dr. Gonzalo Luis Alonso Salinas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.