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State-of-the-Art Research on the Imaging in Personalized Medicine
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State-of-the-Art Research on the Imaging in Personalized Medicine

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".

Deadline for manuscript submissions: 25 June 2024 | Viewed by 2386

Special Issue Editors

Dr. Nicola Maggialetti

E-Mail Website
Guest Editor
Interdisciplinary Department of Medicine, Section of Radiology and Radiation Oncology, University of Bari “Aldo Moro”, Piazza Giulio Cesare 11, 70124 Bari, Italy
Interests: CT; MRI; oncological imaging; cardiac imaging; US; artificial intelligence; hybrid imaging
Dr. Antonio Rosario Pisani

E-Mail Website
Co-Guest Editor
Interdisciplinary Department of Medicine, Section of Nuclear Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare 11, 70124 Bari, Italy
Interests: nuclear neurology imaging; nuclear gastroenterology imaging; PET/CT; artificial intelligence; nuclear medical radiotherapy

Special Issue Information

Dear Colleagues,

Imaging is an increasingly important discipline in diagnostic and therapeutic processes. The introduction of new technologies such as high-field magnetic resonance imaging, new-generation CT scans and hybrid scanners have provided new impetus for research. Multimodality imaging involves all the nuclear medicine techniques thanks to the hybrid SPECT/CT, PET/CT and PET/MR scanning methods. The development of new materials for endovascular techniques, as well as the availability of more and more radiopharmaceuticals, allows for innovative approaches to be implemented against oncological and non-oncological pathologies. The increasingly widespread use of artificial intelligence programs is extremely important and opens up new scenarios for clinical and research applications of diagnostic imaging. Realizing personalized imaging and increasingly advanced treatments is the challenge that our discipline is currently facing.

Dr. Nicola Maggialetti
Dr. Antonio Rosario Pisani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • MRI
  • CT
  • PET/CT
  • artificial intelligence
  • oncological imaging
  • cardiac imaging
  • hybrid imaging
  • endovascolar radiology
  • radiomics
  • neuroimaging

Published Papers (2 papers)

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Research

19 pages, 5164 KiB  
Article
The Role of the 18F-FDG PET/CT in the Management of Patients Suspected of Cardiac Implantable Electronic Devices’ Infection
by Antonio Rosario Pisani, Dino Rubini, Corinna Altini, Rossella Ruta, Maria Gazzilli, Angela Sardaro, Francesca Iuele, Nicola Maggialetti and Giuseppe Rubini
J. Pers. Med. 2024, 14(1), 65; https://doi.org/10.3390/jpm14010065 - 04 Jan 2024
Viewed by 981
Abstract
Background: Infection of Cardiac Implantable Electronic Devices (CIEDI) is a real public health problem. The main aim of this study was to determine the diagnostic performance of 18F-FDG PET/CT in the diagnosis of CIEDI. Methods: A total of 48 patients, who performed [...] Read more.
Background: Infection of Cardiac Implantable Electronic Devices (CIEDI) is a real public health problem. The main aim of this study was to determine the diagnostic performance of 18F-FDG PET/CT in the diagnosis of CIEDI. Methods: A total of 48 patients, who performed 18F-FDG PET/CT for the clinical suspicion of CIEDI were retrospectively analyzed; all patients were provided with a model with procedural recommendations before the exam. Sensitivity (Se), specificity (Sp), positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy (DA) of 18F-FDG PET/CT were calculated; the reproducibility of qualitative analysis was assessed with Cohen’s κ test. The semi-quantitative parameters (SUVmax, SQR and TBR) were evaluated in CIEDI+ and CIEDI− patients using the Student’ t-test; ROC curves were elaborated to detect cut-off values. The trend of image quality with regards to procedural recommendation adherence was evaluated. Results: Se, Sp, PPV, NPV and DA were respectively 96.2%, 81.8%, 86.2%, 94.7% and 89.6%. The reproducibility of qualitative analysis was excellent (K = 0.89). Semiquantitative parameters resulted statistically different in CIEDI+ and CIEDI− patients. Cut-off values were SUVmax = 2.625, SQR = 3.766 and TBR = 1.29. Trend curves showed increasing image quality due to adherence to procedural recommendations. Conclusions: 18F-FDG-PET/CT is a valid tool in the management of patients suspected of CIEDI and adherence to procedural recommendations improves its image quality. Full article
(This article belongs to the Special Issue State-of-the-Art Research on the Imaging in Personalized Medicine)
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12 pages, 12059 KiB  
Article
The Role of Coronary CT Angiography in the Evaluation of Dual Left Anterior Descending Artery Prevalence and Subtypes: A Retrospective Multicenter Study
by Nicola Maggialetti, Sara Greco, Giovanni Lorusso, Cristiana Mileti, Gabriella Sfregola, Maria Chiara Brunese, Marcello Zappia, Maria Paola Belfiore, Pasquale Sullo, Alfonso Reginelli, Nicola Maria Lucarelli and Arnaldo Scardapane
J. Pers. Med. 2023, 13(7), 1127; https://doi.org/10.3390/jpm13071127 - 12 Jul 2023
Cited by 1 | Viewed by 1000
Abstract
Background: The aim of this multicenter study was to evaluate the prevalence and features of dual left anterior descending artery (LAD) subtypes using coronary CT angiography (CCTA). Methods: A retrospective multicenter analysis of 2083 CCTA from December 2020 to November 2022 was conducted [...] Read more.
Background: The aim of this multicenter study was to evaluate the prevalence and features of dual left anterior descending artery (LAD) subtypes using coronary CT angiography (CCTA). Methods: A retrospective multicenter analysis of 2083 CCTA from December 2020 to November 2022 was conducted to search for the presence and morphological features of dual LAD. The two classifications used were the updated classification of Spindola-Franco and the Jariwala classification. Statistical tests were conducted to evaluate the prevalence of dual LADs among sexes and its association with angina in patients without significant coronary stenoses and/or associated cardiac anomalies. Results: Dual LAD was observed in 124 (5.96%) patients analyzed. According to the Spindola-Franco revisited classification, type I dual LAD was the most common (71/124, 57.26%). According to the Jariwala classification, all cases were group I. In the general population, there was a higher prevalence of dual LAD among females (7.3% females vs. 5.1% males; p value: 0.04). No statistically significant difference was found in the prevalence of angina in the dual LAD population compared to the no dual LAD population (2.1% vs. 1.5%; p value: 0.10). Conclusions: The acknowledgment and reporting of LAD duplication is helpful for an optimal management of coronary patients with this condition. Dual LAD was more frequent in the female population, mainly not related with angina. Myocardial bridge was more frequent in the dual LAD population than in the no dual LAD population. Full article
(This article belongs to the Special Issue State-of-the-Art Research on the Imaging in Personalized Medicine)
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