Advances in Environmental Nanotoxicology—from Traditional Standard Toxicity Tests to the Application of New Approach Methodologies

Dear Colleagues,

Nanotechnology has made significant progress over the past few decades. Nanomaterials (NMs) are currently used across a variety of fields and applications, including healthcare, electronics, energy, environmental protection, and agriculture. However, while the use of NMs has substantial benefits, there are challenges that persist, specifically regarding their safety and regulation. Organizations such as the OECD have been extremely dedicated to harmonizing guidance for the risk assessment of NMs leading to the adaptation of the traditional methods to deal with nano-related specificities. Entities such as the ECHA, EFSA, and OECD are strongly encouraging the inclusion of New Approach Methodologies (NAMs), e.g., computational models, in vitro assays, high-throughput screening, and omics techniques, which can enrich knowledge gaps and the understanding of the unique risks posed by NMs and advanced materials.

This Special Issue invites the submission of original research papers, reviews, short communications, and perspectives that address the environmental effects of NMs and advanced materials, including, nanoparticles, nanoplastics, nanoformulations, nanopesticides, among other related topics. Papers may also include research concerning to NAMs, phenotypic, and behavioral outcomes (e.g., standard tests); toxicokinetic and toxicodynamic studies; the assessment of molecular or epigenetic mechanisms of toxicity; and in vitro studies and predictive or computational toxicology approaches, supported by materials characterization.

Dr. Susana I. L. Gomes
Dr. Mónica J. B. Amorim
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Xenobiotics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• nanomaterials/nanoparticles
• nanoplastics
• nanopesticides/nanoformulations
• risk assessment
• hazard and exposure assessment
• standard tests
• new approach methodologies
• omics
• systems biology