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Advanced Biomaterials and Oral Implantology—Volume II
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Advanced Biomaterials and Oral Implantology—Volume II

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 3861

Special Issue Editors

Dr. Dominik Kraus

E-Mail Website
Guest Editor
Department of Prosthodontics, Preclinical Education and Dental Materials Science, University of Bonn, Bonn, Germany
Interests: oral rehabilitation; biomaterials; periodontitis; implant dentistry
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Norbert Enkling

E-Mail Website
Guest Editor
1. Department of Prosthodontics, Preclinical Education and Dental Materials Science, University of Bonn, Bonn, Germany
2. Department of Reconstructive Dentistry and Gerodontology, Division of Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
Interests: oral rehabilitation; implant dentistry; oral function; oral surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of oral biomaterials has come a long way since Brånemark introduced titanium dental implants and since the concept of biocompatibility first emerged. As for today, a repertoire of customized biomaterials meet the demands of millions of patients worldwide in the realms of both prosthetics and regenerative tissue engineering. Dental implantology as well as alloplastic bone reconstruction rely on a variety of substrate materials along with different designs on the macro level and sophisticated and fine-tuned surface modifications or biochemical functionalizations to meet the requirements of their specific field of application. In many cases, there are no satisfactory alternatives to biomaterial-based oral implants that can produce the same level of long-term functionality.

However, oral implants perform in a complex environment that—besides mechanical stability and esthetics—involves the biological interaction with hard and soft tissues, the immune system and the oral microbiome. While progress has been made in the fields of material sciences, surface biofunctionalization, manufacturing processes and the medical understanding of the involved processes in recent years, a considerable portion of oral implants still exhibit impaired (bone and periodontal) healing or fail in the long run, either due to mechanic failure, deficient tissue integration or peri-implant diseases.

This Special Issue, entitled “Advanced Biomaterials and Oral Implantology—Volume II”, aims to introduce studies that reflect the progress in nanobiomaterials, polymers, drug release and surface functionalization, but also certainly include hot topics within the clinical workflow such as immediate implant placement, immediate restoration and the digital workflow.

The main topics of this Special Issue include, but are not limited to, the following:

  • Advances in substrate materials, e.g., metal, bioceramics, polymers and composites;
  • Macro-/micro implant-surface modifications;
  • Surface functionalization (e.g., drug release, hormones, immobilized antibacterial agents, antimicrobial peptides);
  • Degradable and non-degradable alloplastic bone substitute biomaterials (biomaterial scaffolds, oral tissue engineering and bone regeneration);
  • Loaded bioscaffolds (and implant regenerative medicine/in bone reconstruction/regeneration);
  • Individualized/customized implant fabrication/reconstruction (CAD/CAM) including 3D printing;
  • Clinical workflow: immediate implant placement; immediate loading/restoration; digital workflow; bone management.

Dr. Dominik Kraus
Prof. Dr. Norbert Enkling
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral implants
  • implant surface modifications
  • surface functionalization
  • biomaterials
  • clinical workflow
  • bone regeneration
  • soft tissue integration

Published Papers (3 papers)

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13 pages, 2376 KiB  
Article
One-Piece Mini Dental Implant-Retained Mandibular Overdentures: 10-Year Clinical and Radiological Outcomes of a Non-Comparative Longitudinal Observational Study
by Nicole Schenk, Hristina Bukvic, Martin Schimmel, Samir Abou-Ayash and Norbert Enkling
J. Funct. Biomater. 2024, 15(4), 99; https://doi.org/10.3390/jfb15040099 - 11 Apr 2024
Viewed by 487
Abstract
This study presents the first 10-year follow-up investigation of the implant survival and peri-implant outcomes of one-piece mini dental implants (MDIs) retaining mandibular implant overdentures (IODs), including marginal bone level alterations (ΔMBLs), clinical peri-implant parameters, and complications. Twenty participants with horizontally atrophied mandibles [...] Read more.
This study presents the first 10-year follow-up investigation of the implant survival and peri-implant outcomes of one-piece mini dental implants (MDIs) retaining mandibular implant overdentures (IODs), including marginal bone level alterations (ΔMBLs), clinical peri-implant parameters, and complications. Twenty participants with horizontally atrophied mandibles received complete dentures and four MDIs (diameter 1.8 mm) at baseline. The dentures were converted into IODs with O-ring attachments. The 10-year follow-up comprised a radiological assessment of ΔMBLs, peri-implant parameters, as well as biological and technical complications. Results from a 10-year follow-up of 14 participants showed a 100% implant survival rate for all 56 implants. The mean ΔMBL after 10 years was −1.12 ± 0.80 mm, with 49 implants classified as successful (ΔMBL < 2 mm) and 7 implants with satisfactory survival (ΔMBL 2–4 mm). Time after implant placement significantly influenced ΔMBL, with stable MBLs after 5 years. The prosthetic survival rate after 10 years was 93%. ΔMBLs were not influenced by implant position or gender but were significantly smaller in subjects older than 65 years. Conclusively, one-piece MDIs with O-ring attachments offer a reliable treatment option for horizontally atrophied mandibles after 10 years, with high implant and prosthetic survival rates, potentially benefiting from advanced age regarding peri-implant bone stability. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—Volume II)
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12 pages, 1459 KiB  
Article
An In Vivo Investigation of Non-Metallic vs. Metallic Hand Scalers on Zirconia Implant-Supported Crowns: A Year-Long Analysis of Peri-Implant Maintenance
by Dayna L. Roemermann, Reem Atout, Igor Pesun, Anastasia Kelekis-Cholakis, Chrysi Stavropoulou, Stefan N. Renvert and Rodrigo França
J. Funct. Biomater. 2024, 15(1), 9; https://doi.org/10.3390/jfb15010009 - 23 Dec 2023
Viewed by 1316
Abstract
This study examined whether the degree of abutment surface modification that may occur with regular periodontal instrumentation has a clinical impact in terms of increased plaque accumulation and increased peri-implant tissue inflammation on zirconia implant abutments. Thirteen patients who had zirconia implant crowns [...] Read more.
This study examined whether the degree of abutment surface modification that may occur with regular periodontal instrumentation has a clinical impact in terms of increased plaque accumulation and increased peri-implant tissue inflammation on zirconia implant abutments. Thirteen patients who had zirconia implant crowns were recruited in this randomized clinical trial. Each patient acted as their control and had either the buccal or lingual surface of their screw-retained implant restoration scaled with a metallic scaler and the other surface with a non-metallic scaler at 3, 6, 9, and 12 months. Cytokine testing of the peri-implant crevicular fluid was completed at 0, 3, and 12 months for IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, or IFNγ. Implant crowns were removed at 12 months and evaluated under an atomic force microscope for the average roughness (Ra). The implant crowns were polished and re-inserted. The results were analyzed using the Kruskal–Wallis test, and post hoc tests were conducted with a significance level of α = 0.05. Significant differences in surface roughness (Ra) were observed between the metallic and non-metallic scalers. The median Ra values were 274.0 nm for metallic scalers and 147.1 nm for non-metallic scalers. However, there were no significant differences between the type of scaler used and the amount of clinical inflammation or cytokine production. Metallic scalers produced deeper, more aggressive surface alterations to the abutment/crown zirconia surface, but there was no statistically significant difference between the degree of surface alterations, amount of BOP, and the amplitude of cytokine inflammation produced. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—Volume II)
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12 pages, 8738 KiB  
Article
Fracture Resistance of a Two-Piece Zirconia Implant System after Artificial Loading and/or Hydrothermal Aging—An In Vitro Investigation
by Ralf-Joachim Kohal, Tim Schikofski, Erik Adolfsson, Kirstin Vach, Sebastian Berthold Maximilian Patzelt, Julian Nold and Gregor Wemken
J. Funct. Biomater. 2023, 14(12), 567; https://doi.org/10.3390/jfb14120567 - 15 Dec 2023
Viewed by 1774
Abstract
The purpose of the present study was to assess the fracture resistance of a two-piece alumina-toughened zirconia implant system with a carbon-reinforced PEEK abutment screw. Methods: Thirty-two implants with screw-retained zirconia abutments were divided into four groups of eight samples each. Group 0 [...] Read more.
The purpose of the present study was to assess the fracture resistance of a two-piece alumina-toughened zirconia implant system with a carbon-reinforced PEEK abutment screw. Methods: Thirty-two implants with screw-retained zirconia abutments were divided into four groups of eight samples each. Group 0 (control group) was neither loaded nor aged in a chewing simulator; group H was hydrothermally aged; group L was loaded with 98 N; and group HL was subjected to both hydrothermal aging and loading in a chewing simulator. One sample of each group was evaluated for t-m phase transformation, and the others were loaded until fracture. A one-way ANOVA was applied to evaluate differences between the groups. Results: No implant fracture occurred during the artificial chewing simulation. Furthermore, there were no statistically significant differences (p > 0.05) between the groups in terms of fracture resistance (group 0: 783 ± 43 N; group H: 742 ± 43 N; group L: 757 ± 86 N; group HL: 740 ± 43 N) and bending moment (group 0: 433 ± 26 Ncm; group H: 413 ± 23 Ncm; group L: 422 ± 49 Ncm; group HL: 408 ± 27 Ncm). Conclusions: Within the limitations of the present investigation, it can be concluded that artificial loading and hydrothermal aging do not reduce the fracture resistance of the investigated implant system. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—Volume II)
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