Advanced Biomaterials and Oral Implantology—3rd Edition

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 31 August 2025 | Viewed by 1671

Special Issue Editors


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Guest Editor
Department of Prosthodontics, Preclinical Education and Dental Materials Science, University of Bonn, Bonn, Germany
Interests: oral rehabilitation; biomaterials; periodontitis; implant dentistry
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Prosthodontics, Preclinical Education and Dental Materials Science, University of Bonn, Bonn, Germany
2. Department of Reconstructive Dentistry and Gerodontology, Division of Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland
Interests: oral rehabilitation; implant dentistry; oral function; oral surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of oral biomaterials has come a long way since Brånemark introduced titanium dental implants and since the concept of biocompatibility first emerged. As for today, a repertoire of customized biomaterials meet the demands of millions of patients worldwide for both prosthetics and regenerative tissue engineering. Dental implantology and alloplastic bone reconstruction rely on varied substrate materials, along with different designs at the macro- level and sophisticated and fine-tuned surface modifications or biochemical functionalizations, to meet the requirements of their specific fields of application. In many cases, there are no alternatives to biomaterial-based oral implants that can produce the same level of long-term functionality.

However, oral implants perform in a complex environment that—besides mechanical stability and esthetics—involves biological interaction with hard and soft tissues, the immune system and the oral microbiome. While progress has been made in the fields of material sciences, surface biofunctionalization, manufacturing processes, and medical understanding of the involved processes in recent years, many oral implants still exhibit impaired (bone and periodontal) healing or fail in the long run, either due to mechanic failure, deficient tissue integration, or peri-implant diseases.

This Special Issue, entitled “Advanced Biomaterials and Oral Implantology—3rd Edition”, will introduce studies that reflect progress in nanobiomaterials, polymers, drug release and surface functionalization, as well as cover hot topics within the clinical workflow such as immediate implant placement, immediate restoration and the digital workflow.

The main topics of this Special Issue include, but are not limited to, the following:

  • Advances in substrate materials, e.g., metal, bioceramics, polymers, and composites;
  • Macro-/micro-implant surface modifications;
  • Surface functionalization (e.g., drug release, hormones, immobilized antibacterial agents, antimicrobial peptides);
  • Degradable and non-degradable alloplastic bone substitute biomaterials (biomaterial scaffolds, oral tissue engineering and bone regeneration);
  • Loaded bioscaffolds (and implant regenerative medicine/in bone reconstruction/regeneration);
  • Individualized/customized implant fabrication/reconstruction (CAD/CAM) including 3D printing;
  • Clinical workflow: immediate implant placement, immediate loading/restoration, digital workflow, and bone management.

Dr. Dominik Kraus
Prof. Dr. Norbert Enkling
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral implants
  • implant surface modifications
  • surface functionalization
  • biomaterials
  • clinical workflow
  • bone regeneration
  • soft tissue integration

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Published Papers (2 papers)

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Research

15 pages, 5359 KiB  
Article
Biomechanical Evaluation of a Novel Non-Engaging Abutment and Screw in Internal Implant Systems: Comparative Fatigue and Load Testing
by Su-Min Cho, Soo-Hwan Byun, So-Yee Ahn, Hyun-Sook Han, Sung-Woon On, Sang-Yoon Park, Sang-Min Yi, In-Young Park, Byoung-Eun Yang and Lee-Kyoung Kim
J. Funct. Biomater. 2025, 16(3), 107; https://doi.org/10.3390/jfb16030107 - 19 Mar 2025
Viewed by 637
Abstract
Dental implants rely on precise prosthetic design and biomechanical stability to ensure long-term success. This study evaluates the mechanical performance of non-engaging abutments in multi-unit combined screw- and cement-retained prostheses (CSCRP) using two internal implant systems: the BlueDiamond (BD) and AnyOne (AO) systems. [...] Read more.
Dental implants rely on precise prosthetic design and biomechanical stability to ensure long-term success. This study evaluates the mechanical performance of non-engaging abutments in multi-unit combined screw- and cement-retained prostheses (CSCRP) using two internal implant systems: the BlueDiamond (BD) and AnyOne (AO) systems. Unlike conventional implant systems that utilize the same type of screw for both engaging and non-engaging abutments, the BD system employs a distinct screw design for non-engaging abutments. A total of 80 implants were tested, with 40 in each group. Mechanical testing included static compressive load and fatigue tests following ISO 14801 standards. The BD system demonstrated significantly higher compressive strength (326.32 kgf vs. 231.82 kgf, p < 0.001) and 23.4% greater fatigue strength compared to the AO system. Precision fit analysis confirmed no significant deformation, microcracks, or fractures after 5 million loading cycles. These findings suggest that the BD system’s unique screw design for non-engaging abutments contributes to improved mechanical performance and durability. Further clinical studies are needed to assess the long-term implications of this design on prosthetic stability and implant longevity. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—3rd Edition)
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19 pages, 6726 KiB  
Article
Intraoperative Profiling of the Supracrestal Implant Complex Minimizes Peri-Implant Crestal Bone Remodeling: The Guided Bone Profiling Concept
by Milan Stoilov, Joerg Winterhoff, Lea Stoilov, Anastasia Timoschenko, Helmut Stark, Florian Heuser, Michael Marder, Dominik Kraus and Norbert Enkling
J. Funct. Biomater. 2025, 16(3), 93; https://doi.org/10.3390/jfb16030093 - 8 Mar 2025
Viewed by 841
Abstract
(1) Background: Early-stage bone resorption following implant placement can significantly impact the long-term success of implants. This study evaluates whether a fully digitally planned implant position based on the E-point concept, along with guided profiling of the supracrestal complex, contributes to improved stability [...] Read more.
(1) Background: Early-stage bone resorption following implant placement can significantly impact the long-term success of implants. This study evaluates whether a fully digitally planned implant position based on the E-point concept, along with guided profiling of the supracrestal complex, contributes to improved stability of peri-implant bone levels. (2) Methods: 29 implants were placed in 27 patients utilizing both immediate (Group 1; n = 19) and delayed placement (Group 2; n = 10) protocols. Implant position and emergence profile were preoperatively determined and consistently executed through guided surgery and CAD/CAM-fabricated restorations. Due to the subcrestal positioning of the implant, a corresponding bone profiler with a guide pin was used to shape the emergence profile and prevent the provisional restoration from impinging on the proximal bone. Provisional restorations were immediately placed to support the emergence profile. Bone level changes were documented radiographically over a two-year period. The first Bone-to-Implant Contact Level (∆ fBIC), change in highest approximal Bone Level (∆ haBL), and formation of an emergence profile width (WEP) were measured. (3) Results: All implants and restorations survived after two years, no significant change in first Bone-to-Implant Contact Level (∆ fBIC = 0 ± 0.02 mm), no change in highest approximal Bone Level (∆ haBL) of −0.23 mm ± 0.71 mm, and formation of an emergence profile width (WEP) averaging 0.18 ± 0.19 mm. (4) Conclusions: Despite the initial stress on the bone caused by bone profiling, guided implant placement and bone shaping, supported by an immediate provisional, have a positive effect on peri-implant bone stability. Full article
(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—3rd Edition)
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