Advanced Nanocarrier for Drug Delivery and Controlled Release: Innovations and Clinical Applications
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Drug Delivery".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 310
Editors
Interests: biomaterials; nanotechnology; tissue regeneration; EMF for health; cell–material interactions; stimuli-responsive materials; computational material science; hydrogel
Special Issues, Collections and Topics in MDPI journals
Interests: cell membranes; computational biomaterial design; molecular modeling; lipids; nanoparticles; membrane-active peptides and proteins
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The field of nanocarrier-based drug delivery has undergone rapid evolution over the past two decades, enabling unprecedented control over drug loading, targeting, and release kinetics. Advanced nanocarriers—including polymeric, lipid-based, inorganic, hybrid, and stimuli-responsive systems—have demonstrated the potential to overcome key limitations of conventional therapeutics, such as poor bioavailability, systemic toxicity, and lack of spatial and temporal control.
In this Special Issue, we welcome the submission of original research articles and reviews that address, but are not limited to, the following topics:
- Design and engineering of advanced nanocarriers for drug delivery and controlled release, including polymeric, lipid-based, inorganic, and hybrid systems;
- Stimuli-responsive and smart nanocarriers activated by external or internal triggers (e.g., magnetic fields, ultrasound, light, pH, redox conditions, or enzymes);
- Mechanisms of controlled, triggered, and site-specific drug release/targeting at the nano–bio interface;
- Computational modeling and multiphysics simulations of nanocarrier behavior under external fields (e.g., electromagnetic, acoustic, and thermal), including transport, activation, and release kinetics;
- In silico design and optimization of nanocarriers and treatment parameters for personalized or precision medicine applications;
- Data-driven and AI-assisted approaches for predicting nanocarrier performance, biodistribution, and therapeutic outcomes;
- Multifunctional and theranostic nanocarriers integrating therapeutic and diagnostic capabilities;
- Interactions of nanocarriers with biological environments, including protein corona formation, immune response, and biodistribution;
- Integration of experimental and computational approaches for rational nanocarrier development;
- Preclinical validation of nanocarrier systems in relevant in vitro and in vivo models;
- Emerging clinical applications of nanocarrier-based drug delivery.
Dr. Martina Lenzuni
Prof. Dr. Kai Yang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- advanced nanocarriers
- controlled drug delivery
- stimuli-responsive nanomedicine
- remote-controlled drug release
- computational modeling and simulation
- translational nanomedicine
- AI and nanocarrier design
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