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15th Anniversary of JFB—Bioinspired Materials for Medical Applications
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15th Anniversary of JFB—Bioinspired Materials for Medical Applications

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials and Devices for Healthcare Applications".

Deadline for manuscript submissions: closed (15 November 2025) | Viewed by 3837

Special Issue Editor

Prof. Dr. Anderson de Oliveira Lobo

E-Mail Website
Guest Editor
Department of Materials Engineering, Federal University of Piauí, Teresina, Brazil
Interests: hydroxyapatite; nanoclays; bioprinting; nanofibers; biomimetic scaffolds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The year 2025 marks the 15th anniversary of the Journal of Functional Biomaterials, a peer-reviewed, open access journal containing research relevant to the field of materials for biomedical use. So far, JFB has published more than 1700 papers from more than 9000 authors. We appreciate each author, reviewer, and academic editor whose support has brought us to where we are today.

To celebrate this significant milestone, we are publishing a Special Issue entitled 15th Anniversary of JFB—Bioinspired Materials for Medical Applications. Bioinspired materials are synthetic materials designed to mimic the structure, properties, or functions of natural materials or living organisms. These materials have shown great potential in various medical applications, including tissue engineering, drug delivery, wound healing, surgical devices, and diagnostic tools. By replicating complex biological processes, bioinspired materials can create more effective and biocompatible medical solutions. They offer innovative approaches to enhance patient care, reduce complications, and promote faster recovery while contributing to sustainable medical practices. These materials are revolutionizing the field of biomedicine by offering innovative solutions inspired by nature.

Areas of Interest

  1. Tissue Engineering: the development of materials that promote human tissue regeneration and repair.
  2. Medical Implants: the creation of more biocompatible and durable materials for use in prosthetics and other implantable devices.
  3. Controlled Drug Delivery: the design of systems that allow for the precise and controlled release of drugs in the body.
  4. Three-Dimensional-Printed Biomaterials: applications of 3D printing to create complex and personalized structures for medical use.
  5. Diagnostic Systems: the development of biosensors and other diagnostic devices based on bioinspired materials.

Prof. Dr. Anderson de Oliveira Lobo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioinspired materials
  • tissue engineering
  • medical implants
  • controlled drug delivery
  • three-dimensional-printed biomaterials
  • diagnostic systems

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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14 pages, 2255 KB  
Article
Effects of a Drying Treatment on the Mechanical Properties and Hemodynamic Characteristics of Bovine Pericardial Bioprosthetic Valves
by Xuan Hu, Zhaoming He and Hao Wang
J. Funct. Biomater. 2025, 16(12), 434; https://doi.org/10.3390/jfb16120434 - 25 Nov 2025
Viewed by 424
Abstract
The high incidence of cardiovascular disease and the early failure of bioprosthetic valves due to calcification have driven the development of anti-calcification technologies. As a new storage technology, drying treatment is expected to delay the calcification process by reducing glutaraldehyde residues. However, the [...] Read more.
The high incidence of cardiovascular disease and the early failure of bioprosthetic valves due to calcification have driven the development of anti-calcification technologies. As a new storage technology, drying treatment is expected to delay the calcification process by reducing glutaraldehyde residues. However, the effects of drying treatment on the mechanical properties and valve functions of bovine pericardial materials are still unclear. The objective of this study is to evaluate the influence of drying and rehydration treatments on the mechanical integrity and geometric properties of bovine pericardium and the hemodynamic performance of bioprosthetic valves made with these tissues. Cross-linked bovine pericardial samples (n = 15) were divided into three groups—wet (control group progressed with normal glutaraldehyde), dehydrated (ethanol–glycerol dehydration), and rehydration (saline immersion) groups—and the geometric stability and nonlinear mechanical behaviors of the materials were analyzed via thickness measurements and uniaxial and biaxial tensile tests. Quantitative results showed that thickness remained stable across groups (wet: 0.356 ± 0.052 mm; dry: 0.361 ± 0.053 mm; rehydrated: 0.361 ± 0.053 mm, p > 0.05). Elastic modulus values were preserved (wet: 12.5 ± 1.8 MPa; dry: 13.1 ± 2.0 MPa; rehydrated: 12.7 ± 1.9 MPa, p > 0.05), and anisotropy ratio showed no significant changes (1.53 ± 0.06 vs. 1.57 ± 0.07, p > 0.05). The hemodynamic performance of bioprosthetic valves made with these materials was evaluated in vitro using a pulsating flow simulation. Hemodynamic parameters demonstrated excellent preservation: effective orifice area (wet: 2.625 ± 0.11 cm2; rehydrated: 2.585 ± 0.12 cm2, Δ = 1.5%, p = 0.32) and regurgitation fraction (wet: 39.35 ± 2.9%; rehydrated: 42.78 ± 3.2%, p = 0.15) showed no statistically significant differences. The geometric properties of the material were not significantly changed by the drying treatment, and the material maintained its nonlinear viscoelastic characteristics and anisotropy. The rehydrated bioprosthetic valves did not differ significantly from those in the wet group in terms of the effective orifice area, regurgitation fraction, and transvalvular pressure difference, and the hemodynamic performance remained stable. Full article
(This article belongs to the Special Issue 15th Anniversary of JFB—Bioinspired Materials for Medical Applications)
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Review

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22 pages, 4153 KB  
Review
Bioinspired Soft Machines: Engineering Nature’s Grace into Future Innovations
by Ajay Vikram Singh, Mohammad Hasan Dad Ansari, Arindam K. Dey, Peter Laux, Shailesh Kumar Samal, Paolo Malgaretti, Soumya Ranjan Mohapatra, Madleen Busse, Mrutyunjay Suar, Veronica Tisato and Donato Gemmati
J. Funct. Biomater. 2025, 16(5), 158; https://doi.org/10.3390/jfb16050158 - 28 Apr 2025
Cited by 5 | Viewed by 2897
Abstract
This article explores the transformative advances in soft machines, where biology, materials science, and engineering have converged. We discuss the remarkable adaptability and versatility of soft machines, whose designs draw inspiration from nature’s elegant solutions. From the intricate movements of octopus tentacles to [...] Read more.
This article explores the transformative advances in soft machines, where biology, materials science, and engineering have converged. We discuss the remarkable adaptability and versatility of soft machines, whose designs draw inspiration from nature’s elegant solutions. From the intricate movements of octopus tentacles to the resilience of an elephant’s trunk, nature provides a wealth of inspiration for designing robots capable of navigating complex environments with grace and efficiency. Central to this advancement is the ongoing research into bioinspired materials, which serve as the building blocks for creating soft machines with lifelike behaviors and adaptive capabilities. By fostering collaboration and innovation, we can unlock new possibilities in soft machines, shaping a future where robots seamlessly integrate into and interact with the natural world, offering solutions to humanity’s most pressing challenges. Full article
(This article belongs to the Special Issue 15th Anniversary of JFB—Bioinspired Materials for Medical Applications)
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