Special Issue "Four-dimensional Biofabrication: Stimuli-responsive Mechanisms for Tissue Engineering"

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).

Deadline for manuscript submissions: closed (31 March 2019)

Special Issue Editor

Guest Editor
Dr. Pedro Morouço

Biofabrication RD&i Group, Centre for Rapid and Sustainable Product Development, 2430 Marinha Grande, Portugal
Website | E-Mail
Interests: biofabrication; bioprinting; tissue engineering; bioactive polymers; hydrogels

Special Issue Information

Dear Colleagues,

The main aim of 4D biofabrication is to develop biological 3D structures, which can change their properties (e.g., stiffness, shape, volume) when triggered by a pre-defined stimulus (e.g., electricity, ionic force, light, magnetic field, pH, temperature). However, to be successful, several challenges arise, namely: (i) bioinks must be optimized to achieve successful printing or assembly; (ii) processes must be mechanically designed to obtain robust shape-changing capacity of the constructs; (iii) specific bioreactors for complex tissue function maturation need to be invented; and (iv) evaluation procedures should be defined to examine the functionality response. In this Special Issue, we will include original articles focusing on the development of automated generation of biologically functional products with structural organization, according to the four above-mentioned items. We will also cover a wide range of biofabrication processes (e.g., bioprinting, bioassembly) that bridge the gap from basic science to clinical applications. In addition, living cells, bioactive molecules, biomaterials, cell aggregates such as micro-tissues, or hybrid cell–material constructs, and subsequent tissue maturation processes could also be appropriate. Further, review manuscripts able to stimulate creative thinking will be highlighted.

Dr. Pedro Morouço
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 850 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • smart materials
  • additive manufacturing
  • tissue engineering

Published Papers (1 paper)

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Review

Open AccessFeature PaperReview
4D Printing: The Shape-Morphing in Additive Manufacturing
J. Funct. Biomater. 2019, 10(1), 9; https://doi.org/10.3390/jfb10010009
Received: 7 January 2019 / Revised: 18 January 2019 / Accepted: 21 January 2019 / Published: 22 January 2019
PDF Full-text (228 KB) | HTML Full-text | XML Full-text
Abstract
3D printing of polymers can now be considered as a common processing technology for the development of biomaterials. These can be constituted out of polymeric abiotic material alone or can be co-printed with living cells. However, the adaptive and shape-morphing characteristics cannot be [...] Read more.
3D printing of polymers can now be considered as a common processing technology for the development of biomaterials. These can be constituted out of polymeric abiotic material alone or can be co-printed with living cells. However, the adaptive and shape-morphing characteristics cannot be developed with the rigid, pre-determined structures obtained by 3D printing. In order to produce functional engineered biomaterials, the dynamic properties/characteristics of the living cells must be attained. 4D printing can be envisaged as a route to achieve these goals. This paper intends to give a brief review of the pioneer 4D printing research that has been developed and to present an insight into future research in this field. Full article
J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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