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New Insights into Hepato-Biliary Diseases: Translating Science into Practice

A topical collection in Journal of Clinical Medicine (ISSN 2077-0383). This collection belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

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Editors


E-Mail Website
Collection Editor
CNR Institute of Clinical Physiology, Pisa, Italy
Interests: cell culture; proteomics; biochemistry; lipidomics; 3D in vitro; iPSC; cardiomyocytes; biomarkers

E-Mail Website
Collection Editor
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
Interests: cell biology; biotechnology; smooth muscle

Topical Collection Information

Dear Colleagues,

Hepatobiliary diseases encompass a wide spectrum of disorders of the liver and biliary tract, affecting thousands of people worldwide. Despite significant scientific advances in recent years, these diseases continue to pose major challenges in terms of early diagnosis, personalised treatment, and long-term disease management. This Topical Collection of the Journal of Clinical Medicine, titled “New Insights into Hepato-Biliary Diseases: Translating Science into Practice”, aims to gather high-quality research that addresses key unmet needs and recent breakthroughs in the field, with an emphasis on translational potential and innovative approaches.

In particular, we welcome submissions that explore:

  • Clinically relevant research models (e.g., liver organoids, microfluidic systems, liver-on-a-chip technologies), providing physiologically meaningful alternatives in clinical research. These models have demonstrated strong correlation with human disease mechanisms and clinical outcomes, supporting their growing role in translational medicine.
  • Biomarker discovery and validation for early detection, prognosis, risk stratification, and treatment response.
  • Novel drug targets and treatment strategies, including anti-fibrotic therapies, immunomodulatory agents, and small molecules.
  • Pathogenesis and management of liver and biliary diseases.

This Topical Collection focuses in particular on translational medicine, which bridges clinical research and application, and aims to highlight studies that can improve diagnosis and guide clinicians toward personalised treatment decisions.

We invite original research articles, comprehensive reviews, and perspective pieces from clinicians, researchers, and translational scientists working across disciplines.

Dr. Elisa Ceccherini
Dr. Antonella Cecchettini
Collections Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hepato-biliary diseases
  • biomarkers
  • drug discovery
  • liver organoids and microfluidics
  • pathogenesis

Published Papers

This collection is now open for submission.
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