Oral Cancer Biomarkers
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 6576
Special Issue Editor
2. Biomedical Research Networking Centre on Cancer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain
3. Department of Surgery and Medical-Surgical Specialties, Medicine and Dentistry School, Santiago de Compostela University, Santiago de Compostela, Spain
Interests: liquid biopsy; salivary biomarkers; oral cancer; head and neck cancer; circulating biomarkers; HPV; precision oncology; microRNAs; methylation; cell-free DNA
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oral cancer is the sixth most common cancer worldwide. It is frequently diagnosed in advanced stages and is associated with poor prognosis and a high mortality rate. Patients with locally advanced disease are often treated with a combination of surgery, radiotherapy, and chemotherapy, but this treatment is still controversial due to its high morbidity and mortality rate. Despite the development of multimodal therapeutic strategies, most cases develop recurrences at local and/or regional level and about a third develop distant metastasis. Therefore, it is necessary to know the molecular mechanisms underlying resistance to chemotherapy, which will allow the development of new more effective therapeutic strategies in the treatment of oral cancer. It is known that the molecular profiles of tumors are heterogeneous and dynamic during the course of the disease and treatment. The cellular mosaicism is related to therapy resistance and the ability to metastasize the different subpopulations of cancer cells, which is key for development targets and personalized therapy. The aim of this Special Issue is to gather the recent advances on clinically potential biomarkers to apply a precision oncology in the field of oral cancer. On behalf of the Journal of Clinical Medicine, we are inviting relevant original research, reviews, and short communications related to this topic.
Prof. Dr. María Mercedes Suárez Cunqueiro
Guest Editor
Manuscript Submission Information
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Keywords
- oral cancer
- early diagnosis
- biomarkers
- prognosis
- predictive therapy response
- liquid biopsy
- immunotherapy
- chemoresistance
- metastasis
- precision oncology
- personalized therapy
