Clinical Treatment of Vitreoretinal Disorders: Current Updates and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 2131

Special Issue Editor


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Guest Editor
Department of Ophthalmology, Kansai Medical University, 2-5-1, Shin-machi, Hirakata 573-1191, Japan
Interests: vitreoretinal disorder; vitrectomy; digital assisted vitrectomy; intraoperative optical coherence tomography; diabetic retinopathy; epiretinal membrane

Special Issue Information

Dear Colleagues,

In recent years, vitreoretinal surgery has seen exponential advancements, largely attributed to the development of surgical instruments, ancillary equipment, and the introduction of numerous new surgical techniques. As a result, expectations regarding surgical outcomes and postoperative visual functions have risen. Surgeons are increasingly expected to successfully complete even the most intricate and demanding surgeries with precision and finesse. To meet these escalating expectations, it is imperative not only to enhance the surgeon's individual skills but also to master the use of surgical instruments and ancillary equipment. Additionally, the flexibility to adopt and implement new techniques that leverage these tools is crucial. Therefore, this Special Issue aims to explore the future of vitreoretinal surgery, and we widely encourage authors to submit articles related to the following topics: (a) examination of new techniques in vitreoretinal surgery; (b) novel clinical approaches in vitreoretinal surgery using heads-up surgery; (c) novel clinical approaches to vitreoretinal surgery using intraoperative OCT; (d) new insights and clinical approaches regarding surgical instruments and peripheral devices; and (e) other reports related to vitreoretinal surgery.

Prof. Dr. Hisanori Imai
Guest Editor

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Keywords

  • vitrectomy
  • digital assisted vitrectomy
  • heads-up surgery
  • intraoperative optical coherence tomography
  • minimally invasive vitreoretinal surgery

Published Papers (2 papers)

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10 pages, 5035 KiB  
Article
Relationship between Image Quality and Reproducibility of Surgical Images in 3D Digital Surgery
by Yoshihito Sakanishi, Ayumi Usui-Ouchi, Shuu Morita, Toshiro Sakuma and Nobuyuki Ebihara
J. Clin. Med. 2024, 13(11), 3051; https://doi.org/10.3390/jcm13113051 - 23 May 2024
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Abstract
Objectives: Ophthalmic three-dimensional (3D) digital surgery can reproduce high-definition surgical images; however, 3D digital surgery is limited by recording capacities. We examined the relationship between the minimum image quality required to reproduce surgical images and recording capacity. Methods: Patients who underwent simultaneous vitrectomy [...] Read more.
Objectives: Ophthalmic three-dimensional (3D) digital surgery can reproduce high-definition surgical images; however, 3D digital surgery is limited by recording capacities. We examined the relationship between the minimum image quality required to reproduce surgical images and recording capacity. Methods: Patients who underwent simultaneous vitrectomy and cataract surgery by the same surgeon using a 3D digital surgery system at Juntendo University Urayasu Hospital between February and October 2021 were evaluated. Various quality (Q) and frame rate (FR) settings were used for each case. Four vitreous surgeons evaluated the reproducibility of recorded images of macular manipulation for epiretinal membrane (ERM) and macular hole (MH) cases and those of peripheral retinal manipulation for rhegmatogenous retinal detachment (RRD) cases. The video bitrate and minimum settings required to reproduce surgical images and factors affecting surgical image reproducibility were examined. Results: A total of 129 eyes of 129 patients were observed. The minimum image quality required to reproduce surgical images was 11.67 Mbps. The Q and FR for periretinal processing and Q for macular manipulation affected surgical image reproducibility (p = 0.025, p = 0.019, and p = 0.07, respectively). The minimum recording settings required to obtain highly reproducible images were Q = 3 and FR = 40. The total file size for vitrectomy video recordings with these settings was as compact as 3.17 GB for 28 min. Conclusions: During 3D digital surgery, highly reproducible surgical images can be obtained with a small storage capacity using settings of at least Q = 3 and FR = 40. Full article
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22 pages, 717 KiB  
Review
Recent Advances of Adipose-Tissue-Derived Mesenchymal Stem Cell-Based Therapy for Retinal Diseases
by Lucia Finocchio, Marco Zeppieri, Andrea Gabai, Leopoldo Spadea and Carlo Salati
J. Clin. Med. 2023, 12(22), 7015; https://doi.org/10.3390/jcm12227015 - 9 Nov 2023
Cited by 2 | Viewed by 1600
Abstract
With the rapid development of stem cell research in modern times, stem cell-based therapy has opened a new era of tissue regeneration, becoming one of the most promising strategies for currently untreatable retinal diseases. Among the various sources of stem cells, adipose tissue-derived [...] Read more.
With the rapid development of stem cell research in modern times, stem cell-based therapy has opened a new era of tissue regeneration, becoming one of the most promising strategies for currently untreatable retinal diseases. Among the various sources of stem cells, adipose tissue-derived mesenchymal stem cells (ADSCs) have emerged as a promising therapeutic modality due to their characteristics and multiple functions, which include immunoregulation, anti-apoptosis of neurons, cytokine and growth factor secretion, and antioxidative activities. Studies have shown that ADSCs can facilitate the replacement of dying cells, promote tissue remodeling and regeneration, and support the survival and growth of retinal cells. Recent studies in this field have provided numerous experiments using different preclinical models. The aim of our review is to provide an overview of the therapeutic strategies, modern-day clinical trials, experimental models, and potential clinical use of this fascinating class of cells in addressing retinal disorders and diseases. Full article
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