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Clinical Perspectives in Extracorporeal Membrane Oxygenation (ECMO)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: closed (25 April 2025) | Viewed by 584

Special Issue Editor


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Guest Editor
Trauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan
Interests: cardiopulmonary resuscitation; critical care; resuscitation; emergency treatment; trauma; disaster medicine; acute care surgery

Special Issue Information

Dear Colleagues,

Although previous randomized trials and observational studies have reported conflicting results regarding the impact of the extracorporeal cardiopulmonary resuscitation (ECPR) implementation on survival and neurological outcomes in out-of-hospital cardiac arrest (OHCA) patients without a return of spontaneous circulation (ROSC), the prevalence of ECPR in patients with OHCA has been rapidly increasing worldwide. However, no high-quality evidence exists regarding the clinical benefits of ECPR after OHCA. Therefore, understanding the current and future state of ECPR is a critical step toward effective implementation worldwide. In this subsequent Special Issue of the Journal of Clinical Medicine, we aim to discuss the etiology, pathophysiology, clinical manifestations, diagnostics, and optimal management in treating ECPR patients. Since we would like to attract a global audience, we welcome any contributions from around the world.

Dr. Wataru Takayama
Guest Editor

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Keywords

  • extracorporeal cardiopulmonary resuscitation
  • venoarterial extracorporeal membrane oxygenation
  • out-of-hospital cardiac arrest
  • ECMO
  • return of spontaneous circulation

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Published Papers (1 paper)

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Review

10 pages, 527 KiB  
Review
Extracorporeal Membrane Oxygenation in the Management of Tumor Lysis Syndrome in Children: A Review of Cases
by Zere Aidynbek, Erken Kakenov, Olga Mironova, Karlygash Ydyrysheva, Tatyana Li and Vitaliy Sazonov
J. Clin. Med. 2025, 14(8), 2771; https://doi.org/10.3390/jcm14082771 - 17 Apr 2025
Viewed by 326
Abstract
Background/Objectives: Tumor lysis syndrome (TLS) is a life-threatening oncologic emergency that occurs in pediatric patients undergoing chemotherapy. Severe complications, including acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and cardiogenic shock, may require extracorporeal membrane oxygenation (ECMO) support. Methods: This [...] Read more.
Background/Objectives: Tumor lysis syndrome (TLS) is a life-threatening oncologic emergency that occurs in pediatric patients undergoing chemotherapy. Severe complications, including acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and cardiogenic shock, may require extracorporeal membrane oxygenation (ECMO) support. Methods: This paper is a nonsystematic review of cases that synthesizes available case reports to evaluate the efficacy and outcomes of ECMO in pediatric TLS. Results: A systematic search identified five cases in which ECMO was used with a mean duration of 14 days. Survival rates were favorable and ECMO played a critical role in bridging these patients through multi-organ failure. Conclusions: While ECMO is a viable rescue therapy for severe TLS, associated complications, such as infections, bleeding, and neurological impairment, warrant careful patient selection and management. Future studies should explore standardized guidelines for the use of ECMO in pediatric oncology patients. Full article
(This article belongs to the Special Issue Clinical Perspectives in Extracorporeal Membrane Oxygenation (ECMO))
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