Radiation-Induced Heart Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 5604
Special Issue Editor
Interests: study of the cardiovascular effects of oncological treatments; pathophysiology of cardiovascular diseases; evaluation of valvular pathologies; application of advanced echocardiography techniques (strain imaging; speckle tracking; 3d echocardiography)
Special Issue Information
Dear Colleagues,
Radiotherapy treatment is considered a valuable resource for the treatment of a broad range of solid tumors, such as breast, lung, and esophageal cancer and Hodgkin’s lymphoma. Nevertheless, radiation therapy usually includes ionizing radiation of the surrounding tissue that provides important side effects, especially involving the heart. Cardiovascular toxicity may impair long-term prognosis in cancer survivors. Consequently, careful watching of possible acute and long-term side effects should be a priority in this subset of patients. Indeed, the resulting cardiac disease may appear acutely but very often it develops several years after the irradiation. The main recognized cardiovascular complications related to radiotherapy include pericarditis, coronary artery disease, myocardial infarction, valvular heart disease, rhythm abnormalities, non-ischemic myocardial and conduction system damages, and peripheral artery diseases. Other than conventional cardiovascular risk factors, cumulative dose, daily fraction, and concomitant chemotherapy agents seem to influence the risk of cardiotoxicity after radiotherapy. Finally, it has to be considered that advances in the delivery of chest radiotherapy have reduced heart damage in patients undergoing radiotherapy.
The present Special Issue aims to give insight into the mentioned aspects of cardiovascular side-effects in radiation therapy, highlighting the importance of prevention, new diagnostic techniques to promptly assess cardiotoxicity and cardioprotective therapeutics, incorporating all the elements that are necessary to reduce mortality and morbidity of oncologic patients undergoing radiotherapy.
Prof. Dr. Maurizio Galderisi
Guest Editor
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Keywords
- Radiation therapy
- Radiotherapy-induced cardiovascular disease
- Cardiotoxicity
- Cardiovascular prevention
- Standard and advanced echocardiography
- Cardioprotective therapeutics
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