Journal of Clinical Medicine

Journal Browser

► Journal Browser

Treatment and Prognosis of Spinal Surgery

Share This Special Issue

Special Issue Editors

Dr. Andy Ton

E-Mail Website
Guest Editor

Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Interests: spine surgery; spinal surgery; fracture

Dr. Shane Shahrestani

E-Mail Website
Guest Editor

1. Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
2. Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90033, USA
Interests: neurosurgery; medical devices; nervous System neoplasms; nerve regeneration; peripheral nerve injuries; acoustic neuroma; radiosurgery; facial nerve

Special Issue Information

Dear Colleagues,

The landscape of spinal surgery is continually evolving, with significant advancements in both treatment modalities and prognostic paradigms. This Special Issue focuses on “Treatment and Prognosis of Spinal Surgery”, aiming to consolidate contemporary research surrounding the practice of clinical spinal surgery.

Advancements in operative approaches, such as with minimally invasive techniques (MIS), intraoperative navigation, and robot-assisted surgery have revolutionized treatment paradigms, although further longitudinal, high-quality data are required to substantiate these applications. Additionally, ongoing developments in preoperative planning and refined risk quantification continue to be driven by substantial strides made with machine-learning algorithms and predictive analytics. Such innovative contributions have played a pivotal role in tailoring individualized approaches to improve patient prognosis.

We therefore invite submissions that assess the efficacy of various operative strategies in the context of clinical and patient-reported outcomes (PROs) following spinal surgery. This issue seeks to provide a comprehensive overview of the current state and future directions in the field, offering insights into both established and emerging treatments for optimizing patient care. We welcome original research articles and reviews that contribute to the further understanding of contemporary treatment paradigms and prognostic indicators for patients undergoing spinal surgery.

We look forward to your valuable contributions.

Dr. Andy Ton
Dr. Shane Shahrestani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Benefits of Publishing in a Special Issue

Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.

Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.

Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.

External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.

Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Other

12 pages, 561 KB

Open AccessSystematic Review

A Systematic Review of the Effect of Osteoporosis on Radiographic Outcomes, Complications, and Reoperation Rate in Cervical Deformity

by Ishan Shah, Elizabeth A. Lechtholz-Zey, Mina Ayad, Brandon S. Gettleman, Emily Mills, Hannah Shelby, Andy Ton, William J. Karakash, Apurva Prasad, Jeffrey C. Wang, Ram K. Alluri and Raymond J. Hah

J. Clin. Med. 2025, 14(17), 6196; https://doi.org/10.3390/jcm14176196 - 2 Sep 2025

Viewed by 382

Abstract

Background/Objectives: The purpose of this review was to determine the impact of osteoporosis on outcomes after surgery for cervical deformity. Cervical deformity involves abnormal curvature or misalignment of the cervical spine, often resulting in a significant loss of quality of life and requiring surgical correction. While osteoporosis has been associated with hardware failure including screw loosening and cage migration in spine surgery, its role in cervical deformity remains unclear. Existing studies report mixed findings with regard to postoperative sequelae in patients with osteoporosis undergoing surgical correction of cervical deformity. Methods: A systematic review using PRISMA guidelines and MeSH terms involving spine surgery for cervical deformity and osteoporosis was performed. The Medline (PubMed) database was searched from 1990 to August 2022 using the following terms: “osteoporosis” AND “cervical” AND (“outcomes” OR “revision” OR “reoperation” OR “complication”). This review focused on radiographic outcomes, as well as post-operative complications. Results: Eight studies were included in the final analysis. Three papers assessed risk factors for the development of post-operative distal junctional kyphosis (DJK), but only one found osteoporosis as a predictor for DJK. Although three studies found that osteoporosis was not significantly associated with the incidence of surgical complications, one highlights osteoporosis as a predictor of complications at 90 days postoperatively (p < 0.001) and another associates osteoporosis with overall poor outcomes (p = 0.021). Furthermore, one study assessing the relationship between osteoporosis and reoperation found no association. Conclusions: Overall, our systematic review suggests that in patients undergoing surgery for cervical deformity, osteoporosis is not predictive of the need for reoperation or the development of postoperative complications, such as DJK, dysphagia, superficial infection, and others. These findings highlight the need for further study regarding the role of osteoporosis in surgical correction of cervical deformity. Full article

(This article belongs to the Special Issue Treatment and Prognosis of Spinal Surgery)

► Show Figures

Journal Menu

Journal Browser

Treatment and Prognosis of Spinal Surgery

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Benefits of Publishing in a Special Issue

Published Papers (1 paper)

Other

Further Information

Guidelines

MDPI Initiatives

Follow MDPI