Special Issue "New Insights into the Interactions between Gut Microbiota and Mental Health"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Psychiatry".

Deadline for manuscript submissions: 15 June 2021.

Special Issue Editor

Dr. Erika L. Nurmi
Guest Editor
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles CA, USA
Interests: psychiatric genetics; precision medicine; pharmacogenomics; pharmacomicrobiomics; gut–brain axis

Special Issue Information

Dear Colleagues,

A growing appreciation of the gut–brain axis has led to investigation of the role of gut microbiota in mental health risk and treatment. Rodent models and human data suggest that both the baseline composition of the gut microbial population and active manipulation of bacterial flora may impact psychiatric symptoms. The most well-developed areas of research include mood, anxiety, and stress disorders. Other areas of exploration range from neurodevelopmental disorders, such as autism, schizophrenia, and attention-deficit/hyperactivity disorder, to neurodegenerative disorders. Based on these preliminary studies, interventions aimed at altering the microbiome, mainly through the administration of probiotics and prebiotics, have begun to be tested. More recently, interactions between gut microbiota and commonly prescribed psychopharmacologic agents have been discovered, and effects on treatment outcomes and adverse events have been reported. While our lack of knowledge about what constitutes a “healthy microbiome” and the safety and efficacy of microbiome manipulation have prevented the widespread clinical implementation of microbiome testing or treatment, commercial services that provide microbiome analysis already exist and are likely to grow. Given the current public enthusiasm for and professional controversy around genetic testing to guide psychiatric prescription, it is likely that microbiome testing and manipulation will be an issue for mental health providers in the near future. The present Special Issue aims to review current knowledge, highlight areas of clinical promise and research potential, and introduce future directions to advance the state of the field of gut microbiota in mental health.

Dr. Erika L. Nurmi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • gut microbiota
  • microbiome
  • gut–brain axis
  • probiotics
  • prebiotics
  • psychobiotics

Published Papers

This special issue is now open for submission.
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