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Current Advances in Acute and Chronic Coronary Syndromes
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Current Advances in Acute and Chronic Coronary Syndromes

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (20 December 2023) | Viewed by 7158

Special Issue Editors

Dr. Clara Bonanad

E-Mail Website
Guest Editor
Cardiology Department, Clinic University Hospital of Valencia, 46010 Valencia, Spain
Interests: cardiovascular disease; atrial fibrillation; frailty; elderly; inflammation; residual risk; anticoagulation; antiplatelet; ACS; CCS
Special Issues, Collections and Topics in MDPI journals
Dr. Alberto Cordero

E-Mail Website
Guest Editor
Department of Cardiology, Hospital Universitario de San Juan, Alicante, Spain
Interests: cardiovascular; disease prevention; atherosclerosis; coronary heart disease; cardiology; coronary disease; blood pressure; dyslipidemia
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Following the incredible success of the Special Issue “Current Advances in Acute Coronary Syndrome” https://www.mdpi.com/journal/jcm/topical_collections/Advances_Acute_Coronary_Syndrome, the Editors of the Journal of Clinical Medicine have decided to prepare and publish this new Special Issue.

With the aging of the population and related therapeutic innovations, patients with acute and chronic coronary syndromes are becoming increasingly complex to address, consequently generating evidence in this context regarding the therapeutic level, interventionism, and the impact of geriatric syndromes.

The objective of this Special Issue is to disseminate a wide range of advances in clinical research on Acute and Chronic Coronary Syndromes topics that could support the future of the clinical progress, care and treatment of patients with Acute and Chronic Coronary Syndromes.

Dr. Clara Bonanad
Dr. Alberto Cordero
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • acute coronary syndrome
  • chronic coronary syndromes
  • prognosis
  • revascularization
  • antiplatelets
  • primary and secondary prevention
  • ischemic heart disease
  • biomarkers
  • geriatric cardiology
  • cardiac imaging techniques

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
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Further information on MDPI's Special Issue policies can be found here.

Published Papers (3 papers)

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Research

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14 pages, 626 KiB  
Article
Sex-Related Differences in the Prevalence of Classical, Non-Classical Risk Factors and Management of the Chronic Coronary Syndrome
by Paweł Muszyński, Elżbieta Pawluczuk, Marta Pasławska, Maciej Kowalczuk, Julia Kozakiewicz, Natalia Sot-Muszyńska, Marcin Kożuch and Sławomir Dobrzycki
J. Clin. Med. 2023, 12(23), 7320; https://doi.org/10.3390/jcm12237320 - 26 Nov 2023
Cited by 3 | Viewed by 1898
Abstract
(1) Background: Coronary artery disease (CAD) remains the leading cause of death in both sexes. The male sex is considered a classical atherosclerosis risk factor, whereas females should be protected by hormonal effects until menopause. Although there are known differences in the development, [...] Read more.
(1) Background: Coronary artery disease (CAD) remains the leading cause of death in both sexes. The male sex is considered a classical atherosclerosis risk factor, whereas females should be protected by hormonal effects until menopause. Although there are known differences in the development, type, and prognosis of chronic coronary syndrome (CCS) between both sexes, there are no differences in approach in the guidelines. (2) Methods: The sex-related differences in CAD risk factors, treatment, echocardiographic, and angiographic results were assessed among 3291 patients with CCS. (3) Results: Women were older and had a higher prevalence of hypertension, dyslipidaemia, and diabetes mellitus than men. Women were more often treated conservatively than men. There was no difference in the use of beta-blockers and statins among the sexes. The LDL cholesterol goal was less frequently reached by women. Women were treated less often with aspirin than men, but they were treated more often with angiotensin receptor blockers than men. The left ventricle ejection fraction was higher among females. The number of obstructed vessels was higher in men. (4) Conclusions: Women may be more exposed to the risk factors of CAD than men. Men are diagnosed with CAD earlier, and their prevention and therapy are more efficient. Full article
(This article belongs to the Special Issue Current Advances in Acute and Chronic Coronary Syndromes)
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12 pages, 917 KiB  
Article
Which Biomarker(s) Augment the Diagnostic Value of the Positive Exercise Electrocardiography Test: Systemic Inflammatory Index, Plasma Atherogenic Index, or Monocyte/HDL-C Ratio?
by Gokhan Ergun and Selami Demirelli
J. Clin. Med. 2023, 12(20), 6440; https://doi.org/10.3390/jcm12206440 - 10 Oct 2023
Viewed by 1350
Abstract
The exercise electrocardiography test (EET) is still used before coronary angiography in the diagnosis of chronic coronary syndromes. This study aimed to demonstrate the value of the combination of a positive EET with the systemic inflammatory index (SII), the plasma atherogenic index (PAI), [...] Read more.
The exercise electrocardiography test (EET) is still used before coronary angiography in the diagnosis of chronic coronary syndromes. This study aimed to demonstrate the value of the combination of a positive EET with the systemic inflammatory index (SII), the plasma atherogenic index (PAI), and the monocyte/HDL-C ratio (MHR) in the determination of obstructive coronary artery disease (CAD). This single-center, retrospective study included 540 patients who underwent coronary angiography after ETT. The patients were separated into Group 1, comprising 434 patients with normal coronary arteries and non-obstructive CAD, and Group 2, including 106 with obstructive CAD. In Group 2, the patients were separated into SYNTAX ≤ 22 or ≥23. Glucose, low-density lipoprotein, white blood cells, and MHR were determined to be significantly higher in Group 2 (p < 0.05). According to the multivariate logistic regression analysis, age, gender, diabetes mellitus, and low-density lipoprotein were determined to be independent predictors of CAD. In the ROC curve analysis, a cut-off value of 12 for the MHR in the determination of obstructive CAD had a sensitivity of 60.4% and a specificity of 53.0%. The main result of this study was that a high MHR is an indicator of obstructive CAD in patients with positive EET and suspected CAD. Full article
(This article belongs to the Special Issue Current Advances in Acute and Chronic Coronary Syndromes)
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Review

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16 pages, 1684 KiB  
Review
Inflammation as a New Therapeutic Target among Older Patients with Ischemic Heart Disease
by Daniela Maidana, Andrea Arroyo-Álvarez, Andrea Arenas-Loriente, Guillermo Barreres-Martín, Carles Muñoz-Alfonso, Daznia Bompart Berroteran, Francisca Esteve Claramunt, Regina Blanco del Burgo, Pedro Cepas-Guillén, Sergio Garcia-Blas and Clara Bonanad
J. Clin. Med. 2024, 13(2), 363; https://doi.org/10.3390/jcm13020363 - 9 Jan 2024
Cited by 6 | Viewed by 3405
Abstract
Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation [...] Read more.
Cardiovascular (CV) diseases remain a global health challenge, with ischemic heart disease (IHD) being the primary cause of both morbidity and mortality. Despite optimal pharmacological therapy, older patients with IHD exhibit an increased susceptibility to recurrent ischemic events, significantly impacting their prognosis. Inflammation is intricately linked with the aging process and plays a pivotal role in the evolution of atherosclerosis. Emerging anti-inflammatory therapies have shown promise in reducing ischemic events among high-risk populations. This review aims to explore the potential of targeted anti-inflammatory interventions in improving clinical outcomes and the quality of life for older patients with IHD. Full article
(This article belongs to the Special Issue Current Advances in Acute and Chronic Coronary Syndromes)
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