New Advances in Cardiorenal Syndrome

Dear Colleagues,

Cardiorenal syndrome has become a pressing issue as far as hospitalizations are concerned, even those for chronic heart failure alone incur a subsequent increased risk for end-stage renal disease (ESRD) later on. When using the term cardiorenal syndrome, the coincident diagnoses of chronic or acute heart failure in the presence of chronic kidney disease and/or acute kidney injury are considered as one syndrome, because both organ dysfunctions may affect each other in a vicious cycle. In 2008, a classification of cardiorenal syndrome was introduced, approved by the American Heart Association in 2019, this classification clearly having improved the standards of cardiorenal syndrome. However, validation studies of this classification are lacking, the clinical applicability is questioned, and new developments in the area of cardiorenal syndrome, such as the role of infection, need to be considered.

In a new Special Issue on cardiorenal syndrome, the Journal of Clinical Medicine summarizes new advances in the understanding of the cardiorenal syndrome, highlighting the description, pathophysiological underpinnings and pathomechanisms, every published article expected to add knowledge to the overall picture of cardiorenal syndrome and its therapeutic implications.

Dr. Rainer Ullrich Pliquett
Guest Editor

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